L
Loan Tran
Publications - 6
Citations - 316
Loan Tran is an academic researcher. The author has contributed to research in topics: Fermentation & Biology. The author has an hindex of 2, co-authored 3 publications receiving 133 citations.
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Journal ArticleDOI
Energy conservation associated with ethanol formation from H2 and CO2 in Clostridium autoethanogenum involving electron bifurcation
Johanna Mock,Yanning Zheng,Alexander P. Mueller,San Ly,Loan Tran,Simon Segovia,Shilpa Nagaraju,Michael Köpke,Peter Dürre,Rudolf K. Thauer +9 more
TL;DR: This work investigates the specific activities and cofactor specificities of all relevant oxidoreductases in cell extracts of H2/CO2-grown C. autoethanogenum cells and proposes metabolic schemes that allow the chemiosmotic synthesis of 0.14 to 1.5 mol ATP per mol ethanol synthesized from CO2 and H2.
Journal ArticleDOI
Carbon-negative production of acetone and isopropanol by gas fermentation at industrial pilot scale
Fungmin Liew,Robert Nogle,Tanus Abdalla,Blake J. Rasor,Christina E. Canter,R. Jensen,Lan Wang,Jon Strutz,Payal Chirania,Sashini De Tissera,Alexander P. Mueller,Zhenhua Ruan,Allan Haiming Gao,Loan Tran,Nancy L. Engle,Jason Carl Bromley,James Daniell,Robert J. Conrado,Timothy J. Tschaplinski,Richard J. Giannone,Robert L. Hettich,Ashty S. Karim,Sean Dennis Simpson,Steven D. Brown,Ching Leang,Michael C. Jewett,Michael Koepke +26 more
TL;DR: In this paper , a carbon-negative fermentation route was proposed to produce the industrially important chemicals acetone and isopropanol from abundant, low-cost waste gas feedstocks, such as industrial emissions and syngas.
Journal ArticleDOI
Cell-free prototyping enables implementation of optimized reverse β-oxidation pathways in heterotrophic and autotrophic bacteria
Bastian Vögeli,Luca Schulz,Shivani Garg,Katia Tarasava,James M. Clomburg,Seung Hwan Lee,Aislinn Gonnot,Elamar Hakim Moully,Blaise R. Kimmel,Loan Tran,Hunter Zeleznik,Steven D. Brown,Sean Dennis Simpson,Milan Mrksich,Ashty S. Karim,Michael Koepke,Michael C. Jewett +16 more
TL;DR: In this paper , the reverse β-oxidation (r-BOX) pathway coupled to the Wood-Ljungdahl pathway is optimized and implemented for the synthesis of C4-C6 acids and alcohols.
ReportDOI
Development of a Sustainable Green Chemistry Platform for Production of Acetone and Downstream Drop-in Fuel and Commodity Products Directly From Biomass Syngas Via a Novel Energy Conserving Route in Engineered Acetogenic Bacteria
Timothy J. Tschaplinski,Payal Charania,Nancy L. Engle,Richard J. Giannone,Robert L. Hettich,Dawn M. Klingeman,Suresh Poudel,Zamin Yang,Sean Dennis Simpson,Tanus Abdalla,Steven D. Brown,Christina Canter,Robert Conrado,James Daniell,Asela Dassanayake,Allan Haiming Gao,Rasmus Overgaard Jensen,Michael Koepke,Ching Leang,Fungmin Liew,Shilpa Nagaraju,Robert Nogle,Ryan Tappel,Loan Tran +23 more
Posted ContentDOI
Autotrophic adaptive laboratory evolution of the acetogen Clostridium autoethanogenum delivers the gas-fermenting strain LAbrini with superior growth, products, and robustness
Henri Ingelman,James K. Heffernan,Audrey Harris,Steven D. Brown,Asfand Yar Saqib,Marina Julio Pinheiro,Lorena Azevedo de Lima,Karen Rodriguez Martinez,R. Axayacatl Gonzalez-Garcia,Grant Hawkins,Jim Daleiden,Loan Tran,Hunter Zeleznik,R. Jensen,Vinicio Reynoso,Sean Dennis Simpson,Michael Koepke,Esteban Marcellin,Kaspar Valgepea +18 more
TL;DR: In this paper , the authors used three adaptive laboratory evolution (ALE) strategies to evolve the wild-type model-acetogen C. autoethanogenum to grow faster, without complex nutrients and to be robust in operation of continuous bioreactor cultures.