Lorena Pantano

TL;DR: The bcbioRNASeq package as mentioned in this paper is a Bioconductor package that provides ready-to-render templates, objects and wrapper functions to post-process RNA sequencing output data, facilitating quality control analyses, identification of differentially expressed genes and functional enrichment analyses.

TL;DR: This work evaluated COMPASS against comparable existing tools on small RNA sequencing data set from serum samples of 12 healthy human controls, and COMPASS identified a greater diversity and abundance of small RNA molecules.

TL;DR: In this article , a comparative study of human carotid artery plaques and calcified aortic valves identifies unique drivers of atherosclerosis versus stenotic valve stenosis and implicates extracellular vesicles in advanced cardiovascular calcification.

TL;DR: In this article, the authors performed a high-throughput compound screen in primary human HSC myofibroblasts and identified 19 small molecules that induce HSC inactivation, including the polyether ionophore nanchangmycin (NCMC), which induces lipid reaccumulation while reducing collagen expression, deposition of collagen in the extracellular matrix, cell proliferation, and migration.