L
Loukas Petridis
Researcher at Oak Ridge National Laboratory
Publications - 84
Citations - 2760
Loukas Petridis is an academic researcher from Oak Ridge National Laboratory. The author has contributed to research in topics: Cellulose & Lignin. The author has an hindex of 26, co-authored 77 publications receiving 2009 citations. Previous affiliations of Loukas Petridis include University of Cambridge & University of Tennessee.
Papers
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Journal ArticleDOI
Common processes drive the thermochemical pretreatment of lignocellulosic biomass
Paul Langan,Paul Langan,Loukas Petridis,Loukas Petridis,Hugh O'Neill,Sai Venkatesh Pingali,Marcus Foston,Yoshiharu Nishiyama,Roland Schulz,Roland Schulz,Benjamin Lindner,Benjamin Lindner,B. Leif Hanson,Shane Harton,William T. Heller,Volker S. Urban,Barbara R. Evans,Sandrasegaram Gnanakaran,Arthur J. Ragauskas,Jeremy C. Smith,Jeremy C. Smith,Brian H. Davison +21 more
TL;DR: In this paper, the morphological changes in biomass during steam explosion pretreatment were investigated, showing that cellulose dehydration and lignin-hemicellulose phase separation are the main driving forces for biomass degradation.
Journal ArticleDOI
Mechanism of lignin inhibition of enzymatic biomass deconstruction
Josh V. Vermaas,Loukas Petridis,Xianghong Qi,Roland Schulz,Roland Schulz,Benjamin Lindner,Jeremy C. Smith +6 more
TL;DR: Lignin binds exactly where for industrial purposes it is least desired, providing a simple explanation of why hydrolysis yields increase with lignin removal.
Journal ArticleDOI
Simulation Analysis of the Temperature Dependence of Lignin Structure and Dynamics
TL;DR: The detailed characterization obtained here provides insight at atomic detail into processes relevant to biomass pretreatment for cellulosic ethanol production and general polymer coil-globule transition phenomena.
Journal ArticleDOI
Supercomputer-Based Ensemble Docking Drug Discovery Pipeline with Application to Covid-19.
Atanu Acharya,Rupesh Agarwal,Rupesh Agarwal,Matthew B. Baker,Jerome Baudry,Debsindhu Bhowmik,Swen Boehm,Kendall G. Byler,Samuel Yen-Chi Chen,Leighton Coates,Connor J. Cooper,Connor J. Cooper,Omar Demerdash,Isabella Daidone,John D. Eblen,John D. Eblen,Sally R. Ellingson,Stefano Forli,Jens Glaser,James C. Gumbart,John A. Gunnels,Oscar Hernandez,Stephan Irle,Stephan Irle,Daniel W. Kneller,Andrey Kovalevsky,Jeffrey M. Larkin,Travis J Lawrence,Scott LeGrand,Shih-Hsien Liu,Shih-Hsien Liu,Julie C. Mitchell,Gilchan Park,Jerry M. Parks,Jerry M. Parks,Anna Pavlova,Loukas Petridis,Loukas Petridis,Duncan Poole,Line Pouchard,Arvind Ramanathan,David M. Rogers,Diogo Santos-Martins,Aaron Scheinberg,Ada Sedova,Y. Shen,Y. Shen,Jeremy C. Smith,Jeremy C. Smith,Micholas Dean Smith,Micholas Dean Smith,Carlos Soto,A. Tsaris,Mathialakan Thavappiragasam,Andreas F. Tillack,Josh V. Vermaas,V. Q. Vuong,V. Q. Vuong,Junqi Yin,Shinjae Yoo,Mai Zahran,Laura Zanetti-Polzi +61 more
TL;DR: A supercomputer-driven pipeline for in silico drug discovery using enhanced sampling molecular dynamics (MD) and ensemble docking is presented, including the use of quantum mechanical, machine learning, and artificial intelligence methods to cluster MD trajectories and rescore docking poses.
Journal ArticleDOI
Cosolvent pretreatment in cellulosic biofuel production: effect of tetrahydrofuran-water on lignin structure and dynamics
Micholas Dean Smith,Micholas Dean Smith,Barmak Mostofian,Xiaolin Cheng,Xiaolin Cheng,Loukas Petridis,Charles M. Cai,Charles M. Cai,Charles E. Wyman,Charles E. Wyman,Jeremy C. Smith,Jeremy C. Smith +11 more
TL;DR: In this paper, a novel cosolvent based biomass pretreatment method called CELF (Cosolvent Enhanced Lignocellulosic Fractionation) which employs tetrahydrofuran (THF) in a single phase mixture with water, was found to be highly effective at solubilizing and extracting lignin from lignosic biomass and achieving high yields of fermentable sugars.