L
Lu Sun
Researcher at National Institutes of Health
Publications - 2
Citations - 277
Lu Sun is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Innate immune system & Immune system. The author has an hindex of 2, co-authored 2 publications receiving 194 citations.
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Journal ArticleDOI
TFEB and TFE3 cooperate in the regulation of the innate immune response in activated macrophages
Nunzia Pastore,Owen A. Brady,Heba I. Diab,Jose A. Martina,Lu Sun,Tuong Huynh,Jeong-A Lim,Hossein Zare,Nina Raben,Andrea Ballabio,Rosa Puertollano +10 more
TL;DR: It is determined that TFEB and TFE3 collaborate with each other in activated macrophages and microglia to promote efficient autophagy induction, increased lysosomal biogenesis, and transcriptional upregulation of numerous proinflammatory cytokines.
Journal ArticleDOI
Novel Role of TRPML2 in the Regulation of the Innate Immune Response
TL;DR: In this paper, the authors analyzed TRPML2 expression in different mouse tissues and organs and found that it was predominantly expressed in lymphoid organs and kidney, and showed that the expression was negligible in resting macrophages, and protein levels dramatically increased in response to TLR activation.