Lucie Y. Zhu

TL;DR: In this article, a proximity-dependent biotinylation technique was used to define the location of more than 4,000 proteins in a human cell and almost 36,000 proximal interactions between proteins, including those at the interface of the mitochondria and ER.

TL;DR: An extensive BioID-based proximity map of a human cell, comprising 192 markers from 32 different compartments that identifies 35,902 unique high confidence proximity interactions and localizes 4,145 proteins expressed in HEK293 cells is reported.

TL;DR: In this paper, a BioID-based map of a human cell based on 192 markers from 32 different subcellular compartments, comprising 35,902 high confidence proximity interactions, and defining the intracellular locations of 4,145 unique proteins in HEK 293 cells.

TL;DR: In this paper , the authors combined cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq) and single-cell RNA sequencing (scRNAseq) to classify all cell types within lesions (n=21; 13 symptomatic) to achieve a comprehensive multimodal understanding of the cellular identities of atherosclerosis and their association with clinical pathophysiology.