K
Kento T. Abe
Researcher at University of Toronto
Publications - 34
Citations - 1354
Kento T. Abe is an academic researcher from University of Toronto. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 9, co-authored 15 publications receiving 629 citations. Previous affiliations of Kento T. Abe include Lunenfeld-Tanenbaum Research Institute & Mount Sinai Hospital.
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Journal ArticleDOI
Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients.
Baweleta Isho,Kento T. Abe,Kento T. Abe,Michelle Zuo,Alainna J Jamal,Alainna J Jamal,Bhavisha Rathod,Jenny Wang,Zhijie Li,Gary Chao,Olga L. Rojas,Yeo Myong Bang,Annie Pu,Natasha Christie-Holmes,Christian Gervais,Derek F. Ceccarelli,Payman Samavarchi-Tehrani,Furkan Guvenc,Patrick Budylowski,Angel Li,Aimee Paterson,Feng Yun Yue,Lina María Marín,Lauren Caldwell,Jeffrey L. Wrana,Jeffrey L. Wrana,Karen Colwill,Frank Sicheri,Frank Sicheri,Samira Mubareka,Scott D. Gray-Owen,Steven J. Drews,Walter L. Siqueira,Miriam Barrios-Rodiles,Mario A. Ostrowski,Mario A. Ostrowski,James M. Rini,Yves Durocher,Allison McGeer,Allison McGeer,Allison McGeer,Jennifer L. Gommerman,Anne-Claude Gingras,Anne-Claude Gingras +43 more
TL;DR: It is confirmed that serum and saliva IgG antibodies to SARS-CoV-2 are maintained in the majority of COVID-19 patients for at least 3 months PSO, and IgG responses in saliva may serve as a surrogate measure of systemic immunity to Sars-Cov-2 based on their correlation with serum IgG responds.
Journal ArticleDOI
A proximity-dependent biotinylation map of a human cell.
Christopher D. Go,Christopher D. Go,James D.R. Knight,Archita Rajasekharan,Bhavisha Rathod,Geoffrey G. Hesketh,Kento T. Abe,Kento T. Abe,Ji-Young Youn,Ji-Young Youn,Payman Samavarchi-Tehrani,Hui Zhang,Lucie Y. Zhu,Evelyn Popiel,Jean-Philippe Lambert,Jean-Philippe Lambert,Etienne Coyaud,Etienne Coyaud,Sally W.T. Cheung,Dushyandi Rajendran,Cassandra J. Wong,Hana Antonicka,Laurence Pelletier,Laurence Pelletier,Alexander F. Palazzo,Eric A. Shoubridge,Brian Raught,Brian Raught,Anne-Claude Gingras,Anne-Claude Gingras +29 more
TL;DR: In this article, a proximity-dependent biotinylation technique was used to define the location of more than 4,000 proteins in a human cell and almost 36,000 proximal interactions between proteins, including those at the interface of the mitochondria and ER.
Journal ArticleDOI
A simple protein-based surrogate neutralization assay for SARS-CoV-2.
Kento T. Abe,Zhijie Li,Reuben Samson,Payman Samavarchi-Tehrani,Emelissa J. Valcourt,Heidi Wood,Patrick Budylowski,Alan P. Dupuis,Roxie C. Girardin,Bhavisha Rathod,Jenny Wang,Miriam Barrios-Rodiles,Karen Colwill,Allison McGeer,Samira Mubareka,Jennifer L. Gommerman,Yves Durocher,Mario A. Ostrowski,Kathleen A. McDonough,Michael A. Drebot,Steven J. Drews,James M. Rini,Anne-Claude Gingras +22 more
TL;DR: A safe and efficient protein-based assay for the detection of serum and plasma antibodies that block the interaction of the SARS-CoV-2 spike protein receptor binding domain (RBD) with its receptor, angiotensin-converting enzyme 2 (ACE2).
Posted ContentDOI
A proximity biotinylation map of a human cell
Christopher D. Go,Christopher D. Go,James D.R. Knight,Archita Rajasekharan,Bhavisha Rathod,Geoffrey G. Hesketh,Kento T. Abe,Kento T. Abe,Ji-Young Youn,Payman Samavarchi-Tehrani,Hui Zhang,Lucie Y. Zhu,Evelyn Popiel,Jean-Philippe Lambert,Jean-Philippe Lambert,Etienne Coyaud,Etienne Coyaud,Sally W.T. Cheung,Dushyandi Rajendran,Cassandra J. Wong,Hana Antonicka,Laurence Pelletier,Laurence Pelletier,Brian Raught,Brian Raught,Alexander F. Palazzo,Eric A. Shoubridge,Anne-Claude Gingras,Anne-Claude Gingras +28 more
TL;DR: An extensive BioID-based proximity map of a human cell, comprising 192 markers from 32 different compartments that identifies 35,902 unique high confidence proximity interactions and localizes 4,145 proteins expressed in HEK293 cells is reported.
Journal ArticleDOI
Evaluation of the SARS-CoV-2 Antibody Response to the BNT162b2 Vaccine in Patients Undergoing Hemodialysis.
Kevin Yau,Kento T. Abe,Kento T. Abe,David Naimark,Matthew J. Oliver,Jeffrey Perl,Jerome A. Leis,Shelly Bolotin,Vanessa Tran,Sarah I. Mullin,Ellen Shadowitz,Anny Gonzalez,Tatjana Sukovic,Julie Garnham-Takaoka,Keelia Quinn De Launay,Alyson Takaoka,Sharon E. Straus,Allison McGeer,Christopher T. Chan,Karen Colwill,Anne-Claude Gingras,Anne-Claude Gingras,Michelle A. Hladunewich +22 more
TL;DR: In this paper, the authors evaluated the SARS-CoV-2 antibody response in patients undergoing chronic hemodialysis following 1 vs 2 doses of BNT162b2 COVID-19 vaccination compared with health care workers serving as controls and convalescent serum.