Luis M. Montuenga

TL;DR: An unexpected pro-tumoural function of sVEGFR1-i13 in SQLC tumour cells is revealed, which contributes to their progression and escape from anti-angiogenic therapies.

TL;DR: It is found that lung squamous cell carcinoma (SQCC), which accounts for ~20% of lung cancer, exhibits increased expression of the PI3K subunit PIK3R2, which is at low expression levels in normal tissues.

TL;DR: This work studied expression of PAMP and PAM in normal prostate and prostatic tumors (clinical specimens and human xenograft models) with or without prior androgen‐deprivation therapy and found a wide distribution of both molecules in NE subpopulations of all kinds.

TL;DR: In this paper, the authors summarized all the available data regarding the role of biomarkers in LDCT screening and early stage lung cancer (NSCLC) from a multidisciplinary perspective and highlighted clinical implications, the need to combine risk stratification, clinical data, radiomics, molecular information and artificial intelligence in order to improve clinical decision-making, especially regarding early diagnostics and adjuvant therapy.

TL;DR: Adrenomedullin will be shown to induce both growth promotion or growth suppression depending on the target cell examined and the surrounding nutritional environment in which the analysis was done.