L
Luis M. Montuenga
Researcher at University of Navarra
Publications - 245
Citations - 10844
Luis M. Montuenga is an academic researcher from University of Navarra. The author has contributed to research in topics: Lung cancer & Cancer. The author has an hindex of 48, co-authored 221 publications receiving 9205 citations. Previous affiliations of Luis M. Montuenga include Chartered Institute of Management Accountants & Carlos III Health Institute.
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Journal ArticleDOI
Adrenomedullin prevents apoptosis in prostate cancer cells.
TL;DR: Over-expressed AM in PC-3, DU 145 and LNCaP cells, which were transfected with an expression vector carrying AM demonstrated a protective role against induced apoptosis in prostate cancer cells, and these results may have important implications in prostate Cancer resistance to chemotherapeutic agents.
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Elevated levels of the complement activation product c4d in bronchial fluids for the diagnosis of lung cancer
Daniel Ajona,Cristina Razquin,Maria Dolores Pastor,Maria J. Pajares,Javier Santos García,Felipe Cardenal,Michael Fleischhacker,Maria D. Lozano,Javier J. Zulueta,Bernd Schmidt,Ernest Nadal,Luis Paz-Ares,Luis M. Montuenga,Ruben Pio +13 more
TL;DR: C4d is consistently elevated in bronchial fluids from lung cancer patients and may be used to improve the diagnosis of the disease.
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Molecular profiling of computed tomography screen-detected lung nodules shows multiple malignant features.
Maria J. Pajares,Isabel Zudaire,Maria D. Lozano,Jackeline Agorreta,Gorka Bastarrika,W. Torre,Ana Remirez,Ruben Pio,Javier J. Zulueta,Luis M. Montuenga +9 more
TL;DR: Small early-stage lung cancers resected after detection in a spiral CT-based screening trial reveal malignant molecular features similar to those found in conventionally diagnosed lung cancers, suggesting that the screen-detected cancers are not overdiagnosed.
Journal ArticleDOI
Adrenomedullin inhibits prostate cancer cell proliferation through a cAMP-independent autocrine mechanism
TL;DR: It is demonstrated that AM (either overexpressed or exogenously added) causes an inhibition of prostate cancer cell growth, which does not depend on changes in intracellular cAMP levels, but may be related to ERK1/2 activation.
Journal ArticleDOI
Underlying disease stress augments plasma and tissue adrenomedullin (AM) responses to endotoxin: colocalized increases in AM and inducible nitric oxide synthase within pancreatic islets.
Ted H. Elsasser,James L. Sartin,Alfredo Martínez,S. Kahl,Luis M. Montuenga,Ruben Pio,Ronald Fayer,Mae Jean Miller,Frank Cuttitta +8 more
TL;DR: It is concluded that chronic low level infection potentiates the severity of metabolic perturbations that arise with additive sudden onset immune challenge, as can occur with bacterial toxins.