L
Lukas Kater
Researcher at Ludwig Maximilian University of Munich
Publications - 13
Citations - 456
Lukas Kater is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Ribosome & Biology. The author has an hindex of 7, co-authored 8 publications receiving 264 citations. Previous affiliations of Lukas Kater include Center for Integrated Protein Science Munich.
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Journal ArticleDOI
Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes.
Lukas Kater,Matthias Thoms,Clara Barrio-Garcia,Jingdong Cheng,Sherif Ismail,Yasar Luqman Ahmed,Gert Bange,Dieter Kressler,Otto Berninghausen,Irmgard Sinning,Ed Hurt,Roland Beckmann +11 more
TL;DR: Structural snapshots reveal the order of integration and compaction of the six major 60S domains within early nucleolar 60S particles developing stepwise from the solvent side around the exit tunnel to the central protuberance.
Journal ArticleDOI
Architecture of the Rix1–Rea1 checkpoint machinery during pre-60S-ribosome remodeling
Clara Barrio-Garcia,Matthias Thoms,Dirk Flemming,Lukas Kater,Otto Berninghausen,Jochen Baßler,Roland Beckmann,Ed Hurt +7 more
TL;DR: The cryo-EM structure of a Saccharomyces cerevisiae nucleoplasmic pre-60S particle containing the dynein-related 550-kDa Rea1 AAA+ ATPase and the Rix1 subcomplex is determined, which allows unidirectional progression toward mature ribosomes.
Journal ArticleDOI
Structure of the 80S ribosome-Xrn1 nuclease complex.
Petr Tesina,Elisabeth Heckel,Jingdong Cheng,Micheline Fromont-Racine,Robert Buschauer,Lukas Kater,B. Beatrix,Otto Berninghausen,Alain Jacquier,Thomas Becker,Roland Beckmann +10 more
TL;DR: It is reported that active Xrn1 can directly and specifically interact with the translation machinery, explaining how rapid 5′-to-3′ mRNA degradation is coupled efficiently to its final round of mRNA translation.
Journal ArticleDOI
Construction of the Central Protuberance and L1 Stalk during 60S Subunit Biogenesis.
Lukas Kater,Valentin Mitterer,Matthias Thoms,Matthias Thoms,Jingdong Cheng,Otto Berninghausen,Roland Beckmann,Ed Hurt +7 more
TL;DR: Two nuclear pre-60S intermediates were discovered that represent previously unknown states after Rea1-mediated removal of the Ytm1-Erb1 complex and reveal how the L1 stalk develops from a pre-mature nucleolar to a mature-like nucleoplasmic state.
Journal ArticleDOI
Partially inserted nascent chain unzips the lateral gate of the Sec translocon.
Lukas Kater,Benedikt Frieg,Otto Berninghausen,Holger Gohlke,Holger Gohlke,Roland Beckmann,Alexej Kedrov,Alexej Kedrov +7 more
TL;DR: A cryo‐electron microscopy‐based structure and biochemical data suggest that the partially inserted nascent chain remains highly flexible until it acquires the transmembrane topology.