L
Lynn Marie Trotti
Researcher at Emory University
Publications - 100
Citations - 2985
Lynn Marie Trotti is an academic researcher from Emory University. The author has contributed to research in topics: Narcolepsy & Polysomnography. The author has an hindex of 25, co-authored 89 publications receiving 2211 citations. Previous affiliations of Lynn Marie Trotti include Emory Healthcare.
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Journal ArticleDOI
A genetic risk factor for periodic limb movements in sleep
Hreinn Stefansson,David B. Rye,Andrew A. Hicks,H. Petursson,Andres Ingason,Thorgeir E. Thorgeirsson,Stefan T Palsson,Thordur Sigmundsson,Albert P. Sigurdsson,Ingibjorg Eiriksdottir,Emilia Soebech,Donald L. Bliwise,Joseph M. Beck,Ami Rosen,Salina P. Waddy,Lynn Marie Trotti,Alex Iranzo,Madhav Thambisetty,Gudmundur A. Hardarson,Kristleifur Kristjansson,Larus J. Gudmundsson,Unnur Thorsteinsdottir,Augustine Kong,Jeffrey R. Gulcher,Daniel F. Gudbjartsson,Kari Stefansson +25 more
TL;DR: The inverse correlation of the variant with iron stores is consistent with the suspected involvement of iron depletion in the pathogenesis of the disease and is associated with susceptibility to periodic limb movements in sleep.
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Test-retest reliability of the multiple sleep latency test in narcolepsy without cataplexy and idiopathic hypersomnia.
TL;DR: The multiple sleep latency test demonstrates poor test-retest reliability in a clinical population of patients with central nervous system hypersomnia evaluated in a tertiary referral center.
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Modulation of Vigilance in the Primary Hypersomnias by Endogenous Enhancement of GABAA Receptors
David B. Rye,Donald L. Bliwise,Kathy P. Parker,Lynn Marie Trotti,Prabhjyot Saini,Jacqueline Fairley,Amanda A. H. Freeman,Paul S. García,Paul S. García,Michael J. Owens,James C. Ritchie,Andrew Jenkins +11 more
TL;DR: The current study suggests that one of the “spindle pricks” that puts hypersomnolent subjects to sleep is a substance in CSF that augments inhibitory GABA signaling, a potential new neuropharmacological pathway for a 25-year-old drug.
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Waking up is the hardest thing I do all day: Sleep inertia and sleep drunkenness.
TL;DR: In patients with hypersomnolence disorders, especially but not exclusively idiopathic hypersomnia, a more pronounced period of confusion and sleepiness upon awakening, known as "sleep drunkenness", is common and problematic, and optimal treatment of sleep drunkenness is unknown.
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No increased risk of obstructive sleep apnea in Parkinson’s disease
TL;DR: Daytime sleepiness, snoring, and obesity may not be helpful in identifying OSA in PD, and Severity of OSA is stable across multiple nights in PD patients.