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James C. Ritchie

Researcher at Emory University

Publications -  151
Citations -  7506

James C. Ritchie is an academic researcher from Emory University. The author has contributed to research in topics: Hydrocortisone & Dexamethasone suppression test. The author has an hindex of 47, co-authored 151 publications receiving 7062 citations. Previous affiliations of James C. Ritchie include University of North Carolina at Chapel Hill & University of Michigan.

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Targeted Peptide Measurements in Biology and Medicine: Best Practices for Mass Spectrometry-based Assay Development Using a Fit-for-Purpose Approach

TL;DR: A workshop was held at the National Institutes of Health with representatives from the multiple communities developing and employing targeted MS assays and defined three tiers of assays distinguished by their performance and extent of analytical characterization.
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Alterations in corticotropin-releasing factor-like immunoreactivity in discrete rat brain regions after acute and chronic stress.

TL;DR: The distribution of CRF-LI was determined in 36 rat brain regions by combined radioimmunoassay-micropunch dissection techniques and the effect of stress on CRF -LI was investigated, using a chronic stress model that induces endocrine changes in rats similar to those seen in depressed humans.
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Hypothalamic-pituitary-adrenal axis function in patients with bipolar disorder

TL;DR: The dex/CRH test is abnormal in both remitted and non-remitted patients with bipolar disorder, and is possibly indicative of the core pathophysiological process in this illness.
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The corticotropin-releasing hormone test in patients with posttraumatic stress disorder.

TL;DR: The blunted ACTH response to CRH in PTSD patients is similar to that seen in other psychiatric disorders, such as depression, panic disorder, and anorexia nervosa.
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Lamotrigine in pregnancy: Clearance, therapeutic drug monitoring, and seizure frequency

TL;DR: These novel data contribute to a rational treatment plan and dosing paradigm for lamotrigine use during pregnancy, parturition, and the postpartum period.