M Falco

TL;DR: The results suggest that p73 isoforms may be differentially regulated, with four different isoforms capable of interacting among themselves and with p53 and the relative expression level of each splice variant may modulate p73 transcriptional and growth suppression activities by affecting heterodimer formation.

TL;DR: It is suggested that although pX is able to activate the Ras/Raf-1-signalling pathway, it triggers NF-kappa B activation by an as yet unidentified Raf-1 -independent pathway.

TL;DR: Experiments indicate that B cells themselves seem to be the target for HBsAg-induced suppression of anti-HBs antibody response, and a specific B lymphocyte defect might be involved in the lacking anti- HBs synthesis in chronic HBV patients.

TL;DR: Investigation of anticardiolipin antibodies in a genetically homogeneous group of Italian patients with BD and retinal vasculitis found a high prevalence of AC; AECA were not found in most of the authors' patients.

TL;DR: This work characterized the mechanisms of AP-1 transcription factor activation by pX and, in particular, the role of cellular proteins involved in the intracellular signal transduction of growth-factor receptors and shows that both Ha-ras and Raf-1 are required for pX-induced activation of c-jun transcriptional activity.