C
Clara Balsano
Researcher at University of L'Aquila
Publications - 139
Citations - 5524
Clara Balsano is an academic researcher from University of L'Aquila. The author has contributed to research in topics: Fatty liver & Nonalcoholic fatty liver disease. The author has an hindex of 34, co-authored 124 publications receiving 5068 citations. Previous affiliations of Clara Balsano include National Research Council & French Institute of Health and Medical Research.
Papers
More filters
Journal ArticleDOI
Activation of SAPK/JNK by TNF Receptor 1 Through a Noncytotoxic TRAF2-Dependent Pathway
Gioacchino Natoli,Antonio Costanzo,Angelo Ianni,Dennis J. Templeton,James R. Woodgett,Clara Balsano,Massimo Levrero +6 more
TL;DR: TNF-induced activation of the stress-activated protein kinase (SAPK) was shown to occur through a noncytotoxic TRAF2-dependent pathway, which means SAPK activation occurs through a pathway that is not required for TNF-R1-induced apoptosis.
Journal ArticleDOI
DNA Damage-Dependent Acetylation of p73 Dictates the Selective Activation of Apoptotic Target Genes
Antonio Costanzo,Antonio Costanzo,Paola Merlo,Natalia Pediconi,Marcella Fulco,Vittorio Sartorelli,Philip A. Cole,Giulia Fontemaggi,Maurizio Fanciulli,Louis Schiltz,Giovanni Blandino,Clara Balsano,Massimo Levrero,Massimo Levrero +13 more
TL;DR: The results suggest that DNA damage-induced acetylation potentiates the apoptotic function of p 73 by enhancing the ability of p73 to selectively activate the transcription of proapoptotic target genes.
Journal ArticleDOI
p300 is required for MyoD‐dependent cell cycle arrest and muscle‐specific gene transcription
Pier Lorenzo Puri,Maria Laura Avantaggiati,Clara Balsano,Nianli Sang,Adolf Graessmann,Antonio Giordano,Massimo Levrero,Massimo Levrero +7 more
TL;DR: It is demonstrated that, in differentiating skeletal muscle cells, p300 physically interacts with the myogenic basic helix–loop–helix (bHLH) regulatory protein MyoD at its DNA binding sites, and p300 potentiates MyOD‐ and myogenin‐dependent activation of transcription from E‐box‐containing reporter genes.
Journal ArticleDOI
Differential regulation of E2F1 apoptotic target genes in response to DNA damage
Natalia Pediconi,Alessandra Ianari,Antonio Costanzo,Laura Belloni,Rita Gallo,Letizia Cimino,Antonio Porcellini,Isabella Screpanti,Clara Balsano,Edoardo Alesse,Alberto Gulino,Massimo Levrero,Massimo Levrero +12 more
TL;DR: It is shown that acetylation is required for E2F1 recruitment on the P1p73 promoter and for its transcriptional activation in response to DNA damage, and p73 is identified as an important E 2F1 apoptotic target gene in DNA damage response.
Journal ArticleDOI
Effects of the Olive-Derived Polyphenol Oleuropein on Human Health
Barbara Barbaro,Gabriele Toietta,R. Maggio,Mario Arciello,Mirko Tarocchi,Andrea Galli,Clara Balsano +6 more
TL;DR: The positive impact on human health of oleuropein, the most prevalent polyphenol present in olives, is reviewed and data collected in the laboratory is provided on the role of o Leandropein in counteracting lipid accumulation in a mouse model of non-alcoholic fatty liver disease.