M
M. Silhol
Researcher at French Institute of Health and Medical Research
Publications - 9
Citations - 799
M. Silhol is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Neurotrophic factors & Tropomyosin receptor kinase B. The author has an hindex of 8, co-authored 9 publications receiving 720 citations. Previous affiliations of M. Silhol include University of Montpellier.
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Journal ArticleDOI
Protective effect of BDNF against beta-amyloid induced neurotoxicity in vitro and in vivo in rats.
Sandor Arancibia,M. Silhol,Florent Mouliere,J. Meffre,I. Höllinger,T. Maurice,Lucia Tapia-Arancibia +6 more
TL;DR: BDNF possesses neuroprotective properties against toxic effects of Abeta peptides, and this effect is concluded to be similar to that of previous studies of EMTs.
Journal ArticleDOI
Age-related changes in brain-derived neurotrophic factor and tyrosine kinase receptor isoforms in the hippocampus and hypothalamus in male rats
TL;DR: The expression (mRNAs and proteins) of BDNF and its three specific receptors, in the hippocampus and hypothalamus throughout lifespan in rats were examined to contribute to the reduced plasticity of these regions observed in old rats.
Journal ArticleDOI
Spatial memory training modifies the expression of brain-derived neurotrophic factor tyrosine kinase receptors in young and aged rats
M. Silhol,Sandor Arancibia,Sandor Arancibia,Tangui Maurice,Tangui Maurice,Lucia Tapia-Arancibia,Lucia Tapia-Arancibia +6 more
TL;DR: It is shown that Wistar rats present age-related differences in the levels of BDNF and TrkB isoforms and that spatial learning differentially modifies some of these parameters in the hippocampus.
Journal ArticleDOI
Placental BDNF/TrkB signaling system is modulated by fetal growth disturbances in rat and human.
Sylvain Mayeur,M. Silhol,Emmanuelle Moitrot,Sandrine Barbaux,Carrie V. Breton,Anne Gabory,Daniel Vaiman,Isabelle Dutriez-Casteloot,I. Fajardy,Anne Vambergue,Lucia Tapia-Arancibia,Bruno Bastide,Laurent Storme,Claudine Junien,Didier Vieau,Jean Lesage +15 more
TL;DR: The results show that the placental BDNF/TrkB system is modulated in rats and humans during pregnancies with fetal growth perturbations and is affected by the maternal energetic status.
Journal ArticleDOI
Perinatal undernutrition modifies cell proliferation and brain-derived neurotrophic factor levels during critical time-windows for hypothalamic and hippocampal development in the male rat.
B. Coupe,Isabelle Dutriez-Casteloot,Carrie V. Breton,F. Lefevre,Jérôme Mairesse,Anne Dickes-Coopman,M. Silhol,M. Silhol,Lucia Tapia-Arancibia,Lucia Tapia-Arancibia,Jean Lesage,Didier Vieau +11 more
TL;DR: The results obtained in the present study show that MPU changes the time course of production of BDNF and cell proliferation in specific hippocampal and hypothalamic areas during sensitive developmental windows, suggesting that these early perinatal modifications may have long‐lasting consequences.