M
Maarten Fornerod
Researcher at Netherlands Cancer Institute
Publications - 59
Citations - 8820
Maarten Fornerod is an academic researcher from Netherlands Cancer Institute. The author has contributed to research in topics: Nuclear pore & Nucleoporin. The author has an hindex of 38, co-authored 52 publications receiving 8397 citations. Previous affiliations of Maarten Fornerod include St. Jude Children's Research Hospital & European Bioinformatics Institute.
Papers
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Journal ArticleDOI
CRM1 Is an Export Receptor for Leucine-Rich Nuclear Export Signals
TL;DR: It is concluded that CRM1 is an export receptor for leucine-rich nuclear export signals and a model for the role of RanGTP inCRM1 function and in nuclear export in general is discussed.
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Characterization of the Drosophila melanogaster genome at the nuclear lamina
Helen Pickersgill,Bernike Kalverda,Elzo de Wit,Wendy Talhout,Maarten Fornerod,Bas van Steensel +5 more
TL;DR: This genome-wide analysis gives clear insight into the nature and dynamic behavior of the genome at the nuclear lamina, and implies that intergenic DNA functions in the global organization of chromatin in the nucleus.
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The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88.
Maarten Fornerod,Jan M. van Deursen,Sjozef van Baal,Albert B. Reynolds,Donna S. Davis,K. Gopal Murti,Jack Fransen,Gerard Grosveld +7 more
TL;DR: The oncogenic nucleoporin CAN/Nup214 is essential in vertebrate cells and it is proposed that hCRM1 is a soluble nuclear transport factor that interacts with the NPC, which is a novel nuclear pore complex (NPC) component named Nup88.
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Nucleoporins Directly Stimulate Expression of Developmental and Cell-Cycle Genes Inside the Nucleoplasm
TL;DR: Nuclear pore complexes stimulate developmental and cell-cycle gene expression away from the NPC by interacting with transcriptionally active genes inside the nucleoplasm, in particular those involved in developmental regulation and the cell cycle.
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Nucleocytoplasmic Transport: The Last 200 Nanometers
TL;DR: This paper presents a meta-analyses of the determinants of remission of Alzheimer's disease in mice and shows clear patterns in response to treatment-naïve mice and also investigates the role of “spatially aggregated immune checkpoints”.