M
Mack C. Mitchell
Researcher at University of Texas Southwestern Medical Center
Publications - 85
Citations - 3461
Mack C. Mitchell is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Alcoholic hepatitis & Medicine. The author has an hindex of 28, co-authored 73 publications receiving 3070 citations. Previous affiliations of Mack C. Mitchell include Johns Hopkins Bayview Medical Center & National Institutes of Health.
Papers
More filters
Journal ArticleDOI
Standard Definitions and Common Data Elements for Clinical Trials in Patients With Alcoholic Hepatitis: Recommendation From the NIAAA Alcoholic Hepatitis Consortia
David W. Crabb,Ramon Bataller,Naga Chalasani,Patrick S. Kamath,Michael R. Lucey,Philippe Mathurin,Craig J. McClain,Arthur J. McCullough,Mack C. Mitchell,Timothy R. Morgan,Laura E. Nagy,Svetlana Radaeva,Arun J. Sanyal,Vijay H. Shah,Gyongyi Szabo +14 more
TL;DR: The goal was to reach agreements on recommendations and definitions that could facilitate trial design, and simultaneously be tested by research groups pooling their data, to achieve better uniformity in clinical trials.
Journal ArticleDOI
Budd-Chiari syndrome: etiology, diagnosis and management.
Journal ArticleDOI
Plasma Tumor Necrosis Factor α Predicts Decreased Long‐Term Survival in Severe Alcoholic Hepatitis
Michael E. Felver,E. Mezey,M. McGuire,Mack C. Mitchell,H. F. Herlong,G. A. Veech,Richard L. Veech +6 more
TL;DR: It is concluded that the presence of elevated plasma TNF alpha is a significant predictor of decreased long-term survival in patients with severe alcoholic hepatitis.
Journal ArticleDOI
Extended lamivudine retreatment for chronic hepatitis B: Maintenance of viral suppression after discontinuation of therapy
Jules L. Dienstag,Eugene R. Schiff,Mack C. Mitchell,Donald E. Casey,Norman Gitlin,Trevor Lissoos,Lawrence D. Gelb,Lawrence D. Gelb,Lynn D. Condreay,Lynn Crowther,Marc Rubin,Nathaniel A. Brown +11 more
TL;DR: Up to 18 months of lamivudine therapy was well tolerated, suppressed HBV replication consistently, and tripled the frequency of HBeAg losses observed during brief‐duration therapy; H beAg loss/seroconversion remained durable posttreatment.
Journal ArticleDOI
Alcohol-induced impairment of central nervous system function: behavioral skills involved in driving
TL;DR: Findings are more consistent with a threshold effect for impairment than for impairment at all levels of BAL, and for most behavioral skills, the decrement in performance after alcohol is slight, rarely exceeding 35-50% of the control period.