M
Madeline P. Smoot
Researcher at University of Texas Southwestern Medical Center
Publications - 2
Citations - 238
Madeline P. Smoot is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Cellular respiration & Microbial metabolism. The author has an hindex of 2, co-authored 2 publications receiving 155 citations.
Papers
More filters
Journal ArticleDOI
Microbial Respiration and Formate Oxidation as Metabolic Signatures of Inflammation-Associated Dysbiosis
Elizabeth R. Hughes,Maria G. Winter,Breck A. Duerkop,Luisella Spiga,Tatiane Furtado de Carvalho,Wenhan Zhu,Caroline C. Gillis,Lisa Büttner,Madeline P. Smoot,Cassie L. Behrendt,Sara Cherry,Renato L. Santos,Lora V. Hooper,Sebastian E. Winter +13 more
TL;DR: Bacterial formate oxidation and oxygen respiration are identified as metabolic signatures for inflammation-associated dysbiosis, which is characterized by a reduced abundance of obligate anaerobic bacteria and an expansion of facultative Proteobacteria such as commensal E. coli.
Journal ArticleDOI
Epithelial-Derived Reactive Oxygen Species Enable AppBCX-Mediated Aerobic Respiration of Escherichia coli during Intestinal Inflammation.
Rachael B. Chanin,Maria G. Winter,Luisella Spiga,Elizabeth R. Hughes,Wenhan Zhu,Savannah J. Taylor,Alexandre Arenales,Caroline C. Gillis,Lisa Büttner,Angel G. Jimenez,Madeline P. Smoot,Renato L. Santos,Sebastian E. Winter +12 more
TL;DR: It is concluded that epithelial-derived reactive oxygen species are degraded in the gut lumen, which gives rise to molecular oxygen that supports the aerobic respiration of E. coli through AppBCX-mediated respiration in a catalase-dependent manner.