Magali Frugier

TL;DR: The results showed the production of an abundant class of tRNA-derived small RNAs preferentially restricted to specific isoacceptors and whose production was more accentuated under nutritional stress, favor the idea that tRNA cleavage is unlikely to be the consequence of non-specific degradation but a controlled process, whose biological significance remains to be elucidated.

TL;DR: It is demonstrated that the N‐terminal extension in yeast AspRS participates in tRNA binding and this finding is generalized to eukaryotic class IIb aminoacyl‐tRNA synthetases.

TL;DR: Structural and aminoacylation properties of in vitro transcribed tRNA(Leu(UUR)) are presented and mutational analysis demonstrates that the discriminator base as well as residue A14 are important leucine identity elements, demonstrating that human mitochondrial leucylation is dependent on rules similar to those that apply in Escherichia coli.

TL;DR: What is known about cytosolic and organellar translation in Plasmodium is reviewed and the molecules that have been identified through genome sequencing and post-genomic analysis are discussed.

TL;DR: It is shown that small RNA helices which recapitulate part or all of the acceptor stem of yeast aspartate tRNA are efficiently aminoacylated by cognate class II aspartyl‐tRNA synthetase, and that the contemporary tRNA(Asp) has quantitatively retained the influence of the major signal for aminoacylation in these substrates.