M
Magdalena Juhaszova
Researcher at National Institutes of Health
Publications - 70
Citations - 11536
Magdalena Juhaszova is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Mitochondrion & Medicine. The author has an hindex of 35, co-authored 60 publications receiving 9482 citations. Previous affiliations of Magdalena Juhaszova include Slovak Academy of Sciences & University of Maryland, Baltimore.
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Journal ArticleDOI
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
TL;DR: The mechanism of mitochondrial RIRR highlights the central role of mitochondria-formed ROS, and all of the known ROS-producing sites and their relevance to the mitochondrial ROS production in vivo are discussed.
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Mitochondrial membrane potential.
Ljubava D. Zorova,Vasily A. Popkov,Egor Y. Plotnikov,Denis N. Silachev,Irina B. Pevzner,S. S. Jankauskas,V. A. Babenko,S. D. Zorov,Anastasia V. Balakireva,Magdalena Juhaszova,Steven J. Sollott,Dmitry B. Zorov,Dmitry B. Zorov +12 more
TL;DR: Additional potential mechanisms for which ΔΨm is essential for maintenance of cellular health and viability are proposed and recommendations how to accurately measure ΔΩm in a cell are provided and potential sources of artifacts are discussed.
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Mitochondrial ROS-induced ROS release: an update and review.
TL;DR: R could be a general cell biology phenomenon relevant to the processes of programmed mitochondrial destruction and cell death, and may contribute to other mechanisms of post-ischemic pathologies, including arrhythmias.
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Glycogen synthase kinase-3β mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore
Magdalena Juhaszova,Dmitry B. Zorov,Dmitry B. Zorov,Suhn-Hee Kim,Suhn-Hee Kim,Salvatore Pepe,Salvatore Pepe,Qin Fu,Kenneth W. Fishbein,Bruce D. Ziman,Su Wang,Kirsti Ytrehus,Christopher L. Antos,Eric N. Olson,Steven J. Sollott +14 more
TL;DR: It is shown that reoxygenation after prolonged hypoxia reduces the reactive oxygen species (ROS) threshold for the mitochondrial permeability transition (MPT) in cardiomyocytes and that cell survival is steeply negatively correlated with the fraction of depolarized mitochondria.
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Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1
Hyeung-Jin Jang,Zaza Kokrashvili,Michael J. Theodorakis,Olga D. Carlson,Byung Joon Kim,Jie Zhou,Hyeon Ho Kim,Xiangru Xu,Sic L. Chan,Magdalena Juhaszova,Michel Bernier,Bedrich Mosinger,Robert F. Margolskee,Josephine M. Egan +13 more
TL;DR: Modulating GLP-1 secretion in gut “taste cells” through the same mechanisms used by taste cells of the tongue may provide an important treatment for obesity, diabetes and abnormal gut motility.