Maik Stein

TL;DR: It is emphasized that alternative activation deprives macrophages of control mechanisms that limit mycobacterial growth in vivo, thus supporting intracellular persistence of M. tuberculosis.

TL;DR: The results show that, during chronic pulmonary tuberculosis in mice, the homeostatic chemokine signaling-network contributes to spatial organization of the granulomatous response, which participates in both containment of M. tuberculosis and the latter's dissemination to other organs.

TL;DR: Proper prognostic values of BKV‐specific immune monitoring are suggested to identify those patients at risk of BkV‐associated nephropathy and to aid in the management of therapeutic interventions.

TL;DR: The experiments show that heterologous prime-boost vaccination with a defined antigen boost “on top” of a BCG primer provides superior protection against tuberculosis over vaccination with BCG alone.

TL;DR: Analysis of cross‐validation data of the IFN‐γ Elispot assay performed within different European laboratories taking part of the EU RISET consortium shows that assessment of circulating alloreactive memory/effector T cells using an INF‐γElispots can be accurately achieved using the same SOP, Elispots bioreader and experienced technicians in kidney transplantation.