M
Martin Lipp
Researcher at Max Delbrück Center for Molecular Medicine
Publications - 191
Citations - 33116
Martin Lipp is an academic researcher from Max Delbrück Center for Molecular Medicine. The author has contributed to research in topics: C-C chemokine receptor type 7 & Chemokine receptor. The author has an hindex of 76, co-authored 191 publications receiving 31421 citations. Previous affiliations of Martin Lipp include Heidelberg University & University of Tokyo.
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Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
TL;DR: It is shown that expression of CCR7, a chemokine receptor that controls homing to secondary lymphoid organs, divides human memory T cells into two functionally distinct subsets, which are named central memory (TCM) and effector memory (TEM).
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CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs.
Reinhold Förster,Andreas Schubel,Dagmar Breitfeld,Elisabeth Kremmer,Ingrid Renner-Müller,Eckhard Wolf,Martin Lipp +6 more
TL;DR: In this paper, the chemokine receptor CCR7 was identified as an important organizer of the primary immune response in mice, and severely delayed kinetics regarding the antibody response and lack contact sensitivity and delayed type hypersensitivity reactions.
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Follicular B Helper T Cells Express Cxc Chemokine Receptor 5, Localize to B Cell Follicles, and Support Immunoglobulin Production
Dagmar Breitfeld,Lars Ohl,Elisabeth Kremmer,Joachim W. Ellwart,Federica Sallusto,Martin Lipp,Reinhold Förster +6 more
TL;DR: In this article, expression of CXC chemokine receptor 5 (CXCR5) defines a novel subpopulation of B helper T cells localizing to follicles, based on the characteristic localization within secondary lymphoid organs.
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A chemokine-driven positive feedback loop organizes lymphoid follicles
K M Ansel,Vu N. Ngo,P. L. Hyman,Sanjiv A. Luther,Reinhold Förster,Jonathon D. Sedgwick,Jeffrey L. Browning,Martin Lipp,Jason G. Cyster +8 more
TL;DR: It is established that B-lymphocyte chemoattractant (BLC/BCA1) and its receptor, CXCR5, are needed for B-cell homing to follicles in lymph nodes as well as in spleen, and that BLC is required for the development of most lymph nodes and Peyer's patches.
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Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming.
Alfonso Martín-Fontecha,Lindy L. Thomsen,Sara Brett,Craig Gerard,Martin Lipp,Antonio Lanzavecchia,Federica Sallusto +6 more
TL;DR: It is shown in mice that natural killer (NK) cells are rapidly recruited in a CCR7-independent, CXCR3-dependent manner to lymph nodes on stimulation by the injection of mature DCs, and an induced pathway of NK cell migration in antigen-stimulated lymph nodes is identified.