M
Malgorzata Kloc
Researcher at Houston Methodist Hospital
Publications - 203
Citations - 6535
Malgorzata Kloc is an academic researcher from Houston Methodist Hospital. The author has contributed to research in topics: Xenopus & Somatic cell. The author has an hindex of 38, co-authored 180 publications receiving 5795 citations. Previous affiliations of Malgorzata Kloc include University of Texas at Austin & University of Texas Health Science Center at Houston.
Papers
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Journal ArticleDOI
Apoptotic Phosphorylation of Histone H2B Is Mediated by Mammalian Sterile Twenty Kinase
Wang L. Cheung,Kozo Ajiro,Kumiko Samejima,Malgorzata Kloc,Peter Cheung,Craig A. Mizzen,Alexander Beeser,Laurence D. Etkin,Jonathan Chernoff,William C. Earnshaw,C. David Allis +10 more
TL;DR: It is reported that phosphorylation of histone H2B at serine 14 (S14) correlates with cells undergoing programmed cell death in vertebrates and provides evidence for a potential apoptotic "histone code."
Journal ArticleDOI
Mechanisms of Subcellular mRNA Localization
TL;DR: Localization of RNA is a widespread and efficient way to target gene products to a specific region of a cell or embryo to regulate the movement and anchoring of different transcripts.
Journal ArticleDOI
Two distinct pathways for the localization of RNAs at the vegetal cortex in Xenopus oocytes
TL;DR: A novel mechanism of translocation and RNA sorting used by RNAs several of which may be involved in the establishment of the embryonic body axis is demonstrated.
Journal ArticleDOI
Joint action of two RNA degradation pathways controls the timing of maternal transcript elimination at the midblastula transition in Drosophila melanogaster.
Arash Bashirullah,Susan R. Halsell,Ramona L. Cooperstock,Malgorzata Kloc,Angelo Karaiskakis,William W. Fisher,Weili Fu,Jill K. Hamilton,Laurence D. Etkin,Howard D. Lipshitz,Howard D. Lipshitz +10 more
TL;DR: In the early embryo of Drosophila melanogaster, there are two independent RNA degradation pathways, either of which is sufficient for transcript elimination, however, only the concerted action of both pathways leads to elimination of transcripts with the correct timing, at the MBT.
Book ChapterDOI
The Balbiani body and germ cell determinants: 150 years later.
TL;DR: The Balbiani body (Bb) in various animal species is described and it is revealed that the molecular composition of pole plasm, polar granules, nuage, and sponge bodies in Drosophila has been deduced from mutational and functional analyses and indirect genetic approaches.