M
Malka Cohen-Armon
Researcher at Tel Aviv University
Publications - 36
Citations - 1454
Malka Cohen-Armon is an academic researcher from Tel Aviv University. The author has contributed to research in topics: DNA damage & Cancer cell. The author has an hindex of 15, co-authored 32 publications receiving 1342 citations. Previous affiliations of Malka Cohen-Armon include Technion – Israel Institute of Technology & Sheba Medical Center.
Papers
More filters
Journal ArticleDOI
DNA-Independent PARP-1 Activation by Phosphorylated ERK2 Increases Elk1 Activity: A Link to Histone Acetylation
Malka Cohen-Armon,Leonid Visochek,Dana Rozensal,Adi Kalal,Ilona Geistrikh,Ilona Geistrikh,Rodika Klein,Sarit Bendetz-Nezer,Zhong Yao,Rony Seger +9 more
TL;DR: In cortical neurons treated with nerve growth factors and in stimulated cardiomyocytes, PARP-1 activation enhanced ERK-induced Elk1-phosphorylation, core histone acetylation, and transcription of the Elk 1-target gene c-fos constitute evidence for PARp-1 activity within the ERK signal-transduction pathway.
Journal ArticleDOI
Antiphospholipid antibodies permeabilize and depolarize brain synaptoneurosomes.
TL;DR: The possibility that these antibodies interact directly with neuronal tissue by studying the electrophysiological effects of aPL on a brain synaptosoneurosome preparation may explain some of the non-thromboembolic CNS manifestations of the antiphospholipid syndrome.
Journal ArticleDOI
Long-Term Memory Requires PolyADP-ribosylation
Malka Cohen-Armon,Leonid Visochek,Ayelet Katzoff,David Levitan,David Levitan,Abraham J. Susswein,Rodika Klein,Mireille Valbrun,James H. Schwartz +8 more
TL;DR: It is suggested that fast and transient decondensation of chromatin structure by polyADP-ribosylation enables the transcription needed to form long-term memory without strand breaks in DNA.
Journal ArticleDOI
A Fast Signal–Induced Activation of Poly(Adp-Ribose) Polymerase: A Novel Downstream Target of Phospholipase C
S. Homburg,Leonid Visochek,Nava Moran,Françoise Dantzer,Esther Priel,E. Asculai,Dov Schwartz,Varda Rotter,Nava Dekel,Malka Cohen-Armon +9 more
TL;DR: This work presents the first evidence for a fast activation of the nuclear protein poly(ADP-ribose) polymerase (PARP) by signals evoked in the cell membrane, constituting a novel mode of signaling to the cell nucleus.
Journal ArticleDOI
PARP-1 activation in the ERK signaling pathway
TL;DR: PARP-1 activation in the ERK signaling pathway mediates epigenetic mechanisms promoting growth, proliferation and differentiation regulated by the Raf-MEK-ERK phosphorylation cascade.