M
Man Hagiyama
Researcher at Kindai University
Publications - 48
Citations - 830
Man Hagiyama is an academic researcher from Kindai University. The author has contributed to research in topics: Cell adhesion molecule & Cell adhesion. The author has an hindex of 16, co-authored 45 publications receiving 700 citations. Previous affiliations of Man Hagiyama include University of Tokyo & Kobe University.
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Journal ArticleDOI
Gefitinib and Luteolin Cause Growth Arrest of Human Prostate Cancer PC-3 Cells via Inhibition of Cyclin G-Associated Kinase and Induction of miR-630
Minami A. Sakurai,Yuki Ozaki,Daisuke Okuzaki,Yoko Naito,Towa Sasakura,Ayumi Okamoto,Hiroe Tabara,Takao Inoue,Man Hagiyama,Akihiko Ito,Norikazu Yabuta,Hiroshi Nojima +11 more
TL;DR: It is reported that GAK expression is positively correlated with the Gleason score in surgical specimens from prostate cancer patients, and findings suggest that G AK may be a new therapeutic target for prostate cancer and osteosarcoma.
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Upregulation of Notch2 and Six1 Is Associated with Progression of Early-Stage Lung Adenocarcinoma and a More Aggressive Phenotype at Advanced Stages
Takahiro Mimae,Morihito Okada,Man Hagiyama,Yoshihiro Miyata,Yasuhiro Tsutani,Takao Inoue,Yoshinori Murakami,Akihiko Ito +7 more
TL;DR: Paired upregulation of Notch2 and Six1 is a transcriptional aberration that contributes to preinvasive-to-invasive adenocarcinoma progression by inducing epithelial–mesenchymal transition and nuclear atypia.
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Noncontact estimation of intercellular breaking force using a femtosecond laser impulse quantified by atomic force microscopy.
TL;DR: It is suggested that fsLP-IF can be used to break intermolecular and intercellular interactions and estimate the adhesion strength under biologically relevant conditions and when the total impulse at Of is well-defined.
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Enhanced Nerve–Mast Cell Interaction by a Neuronal Short Isoform of Cell Adhesion Molecule-1
Man Hagiyama,Tadahide Furuno,Yoichiroh Hosokawa,Takanori Iino,Takeshi Ito,Takao Inoue,Mamoru Nakanishi,Yoshinori Murakami,Akihiko Ito +8 more
TL;DR: CADM1d is a specific neuronal isoform that enhances nerve–mast cell interaction, and it is suggested that nerve– mast cell interaction may be reinforced as the brain grows mature because CADM1D becomes predominant.
Journal ArticleDOI
Cell Adhesion Molecule 1 Is a Novel Pancreatic–Islet Cell Adhesion Molecule That Mediates Nerve–Islet Cell Interactions
Yu-ichiro Koma,Tadahide Furuno,Man Hagiyama,Kazuyuki Hamaguchi,Mamoru Nakanishi,Mari Masuda,Seiichi Hirota,Hiroshi Yokozaki,Akihiko Ito +8 more
TL;DR: The strong correlation between CADM1 expression and hormonally functional phenotypes suggests that CADM 1 is involved in hormone secretion from ICTs, and is a novel islet cell adhesion molecule mediating nerve-islet cell interactions.