M
Manfred Lindau
Researcher at Cornell University
Publications - 118
Citations - 7331
Manfred Lindau is an academic researcher from Cornell University. The author has contributed to research in topics: Exocytosis & Vesicle. The author has an hindex of 45, co-authored 114 publications receiving 6875 citations. Previous affiliations of Manfred Lindau include Max Planck Society & University of Seville.
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Coarse Grain Simulations Reveal Movement of Synaptobrevin C Terminus in Response to Piconewton Forces Suggesting a Novel Fusion Pore Mechanism
TL;DR: A mechanism where fusion pore formation is induced by movement of the charged syb2 C terminus into the hydrophobic core of the membrane in response to the force generated by C terminal zippering of the SNARE complex is suggested.
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Simultaneous capacitance and calcium measurements in degranulating neutrophils.
O. Nüße,Manfred Lindau +1 more
Journal ArticleDOI
Precise Time Superresolution by Event Correlation Microscopy
TL;DR: The event correlation microscopy method provides time superresolution beyond the photon rate limit and imaging frame duration with well-defined precision, providing guidelines for camera exposure time settings depending on imaging signal properties and camera parameters for optimal time resolution.
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Patch-clamp capacitance measurements: a tool for investigating the second messengers regulating exocytosis.
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AFM/TIRF force clamp measurements of neurosecretory vesicle tethers reveal characteristic unfolding steps.
TL;DR: The frequency of short (<10 nm) tether extension events was markedly higher when a fluorescent vesicle was present at the cantilever tip and increased in the presence of GTPγS, indicating that these events reflect specifically the properties of vesicles-plasma membrane tethers.