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Manfred Lindau

Researcher at Cornell University

Publications -  118
Citations -  7331

Manfred Lindau is an academic researcher from Cornell University. The author has contributed to research in topics: Exocytosis & Vesicle. The author has an hindex of 45, co-authored 114 publications receiving 6875 citations. Previous affiliations of Manfred Lindau include Max Planck Society & University of Seville.

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Surface-modified CMOS IC electrochemical sensor array targeting single chromaffin cells for highly parallel amperometry measurements

TL;DR: Surface-modified CMOS-based electrochemical sensor arrays allow simultaneous recordings from multiple cells and a reliable, low-cost technique is presented here for efficient targeting of single cells specifically to the electrode sites.
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The calcium signal in human neutrophils and its relation to exocytosis investigated by patch-clamp capacitance and Fura-2 measurements.

TL;DR: Different signalling pathways appear to be involved in GTP gamma S- and fMLP-stimulated calcium signals and the intracellular calcium release is not an essential signal to initiate exocytosis in neutrophils.
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The mystery of the fusion pore.

TL;DR: A new study using very small nanodiscs shows that release of neurotransmitters occurs by opening of a fusion pore in a manner thought to be mediated by SNARE proteins, but whether the fusion pores is a lipidic or a proteinaceous structure is controversial.
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GTPγS-induced calcium transients and exocytosis in human neutrophils

TL;DR: The interplay between guanine nucleotides, [Ca2+]in and exocytosis in neutrophils closely resembles previous results obtained in mast cells suggesting a similar regulation of exocyTosis in both cell types.