Showing papers by "Manisha Pal published in 2012"
TL;DR: The study suggested that smoking is associated with altered semen quality, endocrine hormonal status, and number of CAG repeats in the AR gene.
Abstract: This study was conducted as part of an epidemiological survey of 126 nonsmokers and 178 smokers, showing primary infertility residing around Kolkata region of Eastern India. Their lifestyle history including smoking habits along with semen and blood were collected. The study examined the association of cigarette smoking with the risk of infertility, by determining the semen quality, follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone levels, and androgen receptor (AR)-CAG repeat length in a group of smokers compared with a control group (non smokers). Based on conventional WHO criteria, lower sperm motility (P < 0.001) and increased sperm morphological defects (P < 0.0001) were associated with smoking habits. Binary logistic regression analysis for the effect of smoking status on sperm DNA integrity demonstrated significant positive correlation (p = 0.006). Serum FSH and LH levels were higher for smokers compared with non-smokers while the testosterone level decreased significantly ...
100 citations
TL;DR: The association of types of pre-S mutations with particular HBV genotype and clinical outcome in the study population is highlighted and underscores the link between mutation/deletion in HBV/A andHBV/C.
16 citations
TL;DR: In this article, a mixture-amount model was proposed, which is quadratic both in the proportions of mixing components and the amount of mixture, and the optimality of the derived designs in the entire class of competing designs has been investigated through equivalence theorem.
Abstract: The authors propose a mixture-amount model, which is quadratic both in the proportions of mixing components and the amount of mixture. They attempt to find the A- and D-optimal designs for the estimation of the model parameters within a subclass of designs. The optimality of the derived designs in the entire class of competing designs has been investigated through equivalence theorem.
9 citations
TL;DR: In this paper, Mandal et al. considered an additive quadratic mixture model, proposed by Darroch and Waller (1985), when the amount of mixture is taken into account, and obtained the A -optimal designs for the estimation of optimum proportions, adopting the approach of Pal and Mandal (2006).
6 citations
TL;DR: In this article, an inventory model for deteriorating items when demand for the item is dependent on the selling price is studied, where shortages are allowed and backlogged, and price inflation is taken into consideration.
Abstract: The paper studies an inventory model for deteriorating items when demand for the item is dependent on the selling price. Shortages are allowed and backlogged, and price inflation is taken into consideration. Further, it is assumed that the supplier permits the inventory manager to settle his accounts within a given specified time period. Numerical examples are cited to illustrate the model and to study the sensitivity of the model to change in model parameters.
4 citations
TL;DR: In this paper, the authors study a deterministic inventory model with shortages, where only a fraction of the unmet demand is backlogged, and the inventory manager offers a discount on it.
Abstract: In this paper we study a deterministic inventory model with shortages, where only a fraction of the unmet demand is backlogged, and the inventory manager offers a discount on it. Conditions of permissible delay in payments are also taken into account. Numerical examples are cited to illustrate the model.
4 citations
TL;DR: Investigation is carried out when mean response in a mixture experiment is described by a quadratic log contrast model and it is found that in a symmetric subspace of the finite dimensional simplex, there exists a D-optimal design that puts weights at the centroid of the sub-space and the vertices of the experimental domain.
Abstract: Optimal designs for estimating the optimum mixing proportions in a quadratic mixture model was first investigated by Pal and Mandal (2006). In this article, similar investigation is carried out when mean response in a mixture experiment is described by a quadratic log contrast model. It is found that in a symmetric subspace of the finite dimensional simplex, there exists a D-optimal design that puts weights at the centroid of the sub-space and the vertices of the experimental domain. The optimality is checked by numerical computation using Equivalence Theorem.
3 citations
TL;DR: This article attempts to find the A-optimal design for the estimation of the optimum mixing proportions and the optimum amount in a mixture-amount model, which is quadratic both in the proportions of mixing components and the amount of mixture.
Abstract: This article studies a mixture-amount model, which is quadratic both in the proportions of mixing components and the amount of mixture. Using the pseudo-Bayesian approach of Pal and Mandal (2006), it attempts to find the A-optimal design for the estimation of the optimum mixing proportions and the optimum amount.
2 citations