M
Manishkumar Patel
Researcher at Stanford University
Publications - 16
Citations - 1687
Manishkumar Patel is an academic researcher from Stanford University. The author has contributed to research in topics: Stem cell & Luciferase. The author has an hindex of 9, co-authored 13 publications receiving 1606 citations.
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Journal ArticleDOI
In Vivo Visualization of Embryonic Stem Cell Survival, Proliferation, and Migration After Cardiac Delivery
Feng Cao,Shuan Lin,Xiaoyan Xie,Pritha Ray,Manishkumar Patel,Xianzhong Zhang,Micha Drukker,Scott J. Dylla,Andrew J. Connolly,Xiaoyuan Chen,Irving L. Weissman,Sanjiv S. Gambhir,Joseph C. Wu +12 more
TL;DR: This is the first study to characterize ES cells that stably express fluorescence, bioluminescence, and positron emission tomography reporter genes and monitor the kinetics of ES cell survival, proliferation, and migration.
Journal ArticleDOI
Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models
Huiping Liu,Manishkumar Patel,Jennifer A. Prescher,Antonia Patsialou,Dalong Qian,Jiahui Lin,Susanna Wen,Ya Fang Chang,Ya Fang Chang,Michael Bachmann,Yohei Shimono,Piero Dalerba,Maddalena Adorno,Neethan A. Lobo,Janet Bueno,Frederick M. Dirbas,Sumanta Goswami,George Somlo,John S. Condeelis,Christopher H. Contag,Sanjiv S. Gambhir,Michael F. Clarke +21 more
TL;DR: These metastatic cancer models, combined with noninvasive imaging techniques, constitute an integrated approach that could be applied to dissect the molecular mechanisms underlying the dissemination of metastatic CSCs (MCSCs) and to explore therapeutic strategies targeting MCSCs in general or to evaluate individual patient tumor cells and predict response to therapy.
Journal ArticleDOI
Differentiation, Survival, and Function of Embryonic Stem Cell–Derived Endothelial Cells for Ischemic Heart Disease
Zongjin Li,Jenny C. Wu,Ahmad Y. Sheikh,Daniel Kraft,Feng Cao,Xiaoyan Xie,Manishkumar Patel,Sanjiv S. Gambhir,Robert C. Robbins,John P. Cooke,Joseph C. Wu +10 more
TL;DR: This is the first study to track the fate and function of transplanted ESC-ECs in the heart and could become a valuable source of cell therapy for induction of angiogenesis in the treatment of myocardial ischemia.
Journal ArticleDOI
Dual-targeted contrast agent for US assessment of tumor angiogenesis in vivo.
Jürgen K. Willmann,Amelie M. Lutz,Ramasamy Paulmurugan,Manishkumar Patel,Pauline Chu,Jarrett Rosenberg,Sanjiv S. Gambhir +6 more
TL;DR: Dual-targeted contrast-enhanced US directed at both VEGFR2 and alpha(v)beta(3) integrin improves in vivo visualization of tumor angiogenesis in a human ovarian cancer xenograft tumor model in mice.
Journal ArticleDOI
Quantum dot imaging for embryonic stem cells.
Shuan Lin,Xiaoyan Xie,Manishkumar Patel,Yao-Hung Yang,Zongjin Li,Feng Cao,Oliver Gheysens,Yan Zhang,Sanjiv S. Gambhir,Jianghong Rao,Joseph C. Wu +10 more
TL;DR: This is the first demonstration of in vivo multiplex imaging of mouse ES cells labeled with QDs, and it is shown that QD 800 offers greater fluorescent intensity than the other QDs tested.