M
Manju Chandran
Researcher at Singapore General Hospital
Publications - 74
Citations - 2115
Manju Chandran is an academic researcher from Singapore General Hospital. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 17, co-authored 61 publications receiving 1288 citations.
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Journal ArticleDOI
Mechanisms of diabetes mellitus-induced bone fragility
TL;DR: Factors including treatment-induced hypoglycaemia, certain antidiabetic medications with a direct effect on bone and mineral metabolism, as well as an increased propensity for falls, all contribute to the increased fracture risk in patients with diabetes mellitus.
Journal ArticleDOI
Diagnosis and management of bone fragility in diabetes: an emerging challenge
Serge Ferrari,Bo Abrahamsen,Nicola Napoli,Nicola Napoli,Kristina Åkesson,Manju Chandran,R. Eastell,G. El-Hajj Fuleihan,Robert G. Josse,Robert G. Josse,David L. Kendler,Marius E. Kraenzlin,Atsushi Suzuki,D. D. Pierroz,Ann V. Schwartz,William D. Leslie +15 more
TL;DR: An algorithm is proposed for the identification and management of diabetic patients at increased fracture risk and the impact of diabetes drugs on bone as well as the efficacy of osteoporosis treatments in this population of adults with diabetes.
Journal ArticleDOI
Algorithm for the management of patients at low, high and very high risk of osteoporotic fractures
J. A. Kanis,J. A. Kanis,Nicholas C. Harvey,Eugene V. McCloskey,Eugene V. McCloskey,Olivier Bruyère,Nicola Veronese,Mattias Lorentzon,Mattias Lorentzon,Mattias Lorentzon,Cyrus Cooper,Cyrus Cooper,René Rizzoli,Gemma Adib,Nasser M. Al-Daghri,C. Campusano,Manju Chandran,Bess Dawson-Hughes,Kassim Javaid,F. Jiwa,Helena Johansson,Helena Johansson,Joon Kiong Lee,Enwu Liu,Demetrio Messina,O. Mkinsi,Daniel Pinto,Daniel Pinto,Daniel Prieto-Alhambra,Daniel Prieto-Alhambra,Kenneth G. Saag,Weibo Xia,L. Zakraoui,Jean-Yves Reginster,Jean-Yves Reginster +34 more
TL;DR: Guidance is provided in an international setting on the assessment and specific treatment of postmenopausal women at low, high and very high risk of fragility fractures as mentioned in this paper, taking additional account of further categorisation of increased risk of fracture.
Journal ArticleDOI
Cohort study to evaluate the effect of vitamin D, magnesium, and vitamin B 12 in combination on progression to severe outcomes in older patients with coronavirus (COVID-19).
Chuen Wen Tan,Liam Pock Ho,Shirin Kalimuddin,Benjamin Pei Zhi Cherng,Yii Ean Teh,Siew Yee Thien,Hei Man Wong,Paul Jie Wen Tern,Manju Chandran,Jason Wai Mun Chay,Chandramouli Nagarajan,Rehena Sultana,Jenny G. Low,Heng Joo Ng +13 more
TL;DR: A vitamin D / magnesium / vitamin B12 combination in older COVID-19 patients was associated with a significant reduction in the proportion of patients with clinical deterioration requiring oxygen support, intensive care support, or both.
Journal ArticleDOI
Epidemiology of hip fractures in Austria: evidence for a change in the secular trend
H. P. Dimai,Axel Svedbom,Astrid Fahrleitner-Pammer,Thomas R. Pieber,Heinrich Resch,Elisabeth Zwettler,Manju Chandran,F. Borgström +7 more
TL;DR: Since 2006, age-standardized incidence of hip fractures has been declining in the Austrian population aged 50 years and above, a reversal in the secular trend has primarily been driven by a decrease in hip fracture incidence in women.