M
Manju Ghosh
Researcher at All India Institute of Medical Sciences
Publications - 44
Citations - 1995
Manju Ghosh is an academic researcher from All India Institute of Medical Sciences. The author has contributed to research in topics: Locus (genetics) & Allele. The author has an hindex of 18, co-authored 44 publications receiving 1848 citations. Previous affiliations of Manju Ghosh include National Institutes of Health.
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Journal ArticleDOI
Dominant and recessive deafness caused by mutations of a novel gene, TMC1 , required for cochlear hair-cell function
Kiyoto Kurima,Linda M. Peters,Yandan Yang,Saima Riazuddin,Zubair M. Ahmed,Sadaf Naz,Deidre Arnaud,Stacy S. Drury,Jianhong Mo,Tomoko Makishima,Manju Ghosh,P. S N Menon,Dilip Deshmukh,Carole Oddoux,Harry Ostrer,Shaheen N. Khan,Sheikh Riazuddin,Prescott L. Deininger,Lori L. Hampton,Susan L. Sullivan,James F. Battey,Bronya J B Keats,Edward R. Wilcox,Thomas B. Friedman,Andrew J. Griffith +24 more
TL;DR: A locus for dominant deafness is reported, DFNA36, which maps to human chromosome 9q13–21 in a region overlapping the DFNB7/B11 locusfor recessive deafness, and eight mutations in a new gene, transmembrane cochlear-expressed gene 1 (TMC1), are identified.
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Origins and frequencies of SLC26A4 (PDS) mutations in east and south Asians: global implications for the epidemiology of deafness
Hong Joon Park,S. Shahid Shaukat,Xue Zhong Liu,Hahn Sh,Sadaf Naz,Manju Ghosh,Kim Hn,Moon Sk,Satoko Abe,Tukamoto K,Sheikh Riazuddin,Madhulika Kabra,Erdenetungalag R,J Radnaabazar,Shaheen N. Khan,Arti Pandya,Shin-ichi Usami,Walter E. Nance,Edward R. Wilcox,Andrew J. Griffith +19 more
TL;DR: Observation of a diverse allelic series unique to each ethnic group indicates that mutational events at SLC26A4 are common and account for approximately 5% of recessive deafness in south Asians and other populations.
Journal ArticleDOI
Nonsyndromic recessive deafness DFNB18 and Usher syndrome type IC are allelic mutations of USHIC.
Zubair M. Ahmed,Tenesha N. Smith,Saima Riazuddin,Tomoko Makishima,Manju Ghosh,Sirosh Bokhari,P. S. N. Menon,Dilip Deshmukh,Andrew J. Griffith,Sheikh Riazuddin,Thomas B. Friedman,Edward R. Wilcox +11 more
TL;DR: It is concluded that mutations of USHIC can cause both Usher syndrome type IC and nonsyndromic recessive deafness DFNB18.
Journal Article
Risk factors for severe acute lower respiratory tract infection in under-five children.
Shobha Broor,Ravindra Mohan Pandey,Manju Ghosh,R. S. Maitreyi,Rakesh Lodha,Tanu Singhal,S. K. Kabra +6 more
TL;DR: Lack of breast-feeding, upper respiratory infection in mother, upper lungs infection in siblings, severe malnutrition, cooking fuel other than liquid petroleum gas, inappropriate immunization for age and history of LRTI in the family were the significant risk factors associated with ALRTI.
Journal ArticleDOI
Novel mutations of MYO15A associated with profound deafness in consanguineous families and moderately severe hearing loss in a patient with Smith-Magenis syndrome.
Nikki A. Liburd,Manju Ghosh,Saima Riazuddin,Sadaf Naz,Shaheen N. Khan,Zubair M. Ahmed,Sheikh Riazuddin,Yong Liang,P. S. N. Menon,Tenesha N. Smith,Ann C.M. Smith,Ken-Shiung Chen,James R. Lupski,Edward R. Wilcox,Lorraine Potocki,Thomas B. Friedman +15 more
TL;DR: Seven families with profound congenital hearing loss from Pakistan and India with evidence of linkage to DFNB3 at 17p11.2.2 are ascertained and three novel homozygous mutations in MYO15A segregating in three of these families are reported.