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Manuel Ramos-Casals

Researcher at University of Barcelona

Publications -  340
Citations -  24977

Manuel Ramos-Casals is an academic researcher from University of Barcelona. The author has contributed to research in topics: Lupus erythematosus & Antiphospholipid syndrome. The author has an hindex of 79, co-authored 319 publications receiving 20554 citations. Previous affiliations of Manuel Ramos-Casals include University of California, San Diego & Chartered Institute of Management Accountants.

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Morbidity and mortality in systemic lupus erythematosus during a 10-year period: a comparison of early and late manifestations in a cohort of 1,000 patients

TL;DR: In this paper, the authors assessed the frequency and characteristics of the main causes of morbidity and mortality in systemic lupus erythematosus (SLE) during a 10-year period and compared the frequency of early manifestations with those that appeared later in the evolution of the disease.
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Adult haemophagocytic syndrome

TL;DR: Analysis of the genetic and molecular pathophysiology of these syndromes have improved the understanding of the crosstalk between lymphocytes and histiocytes and their regulatoty mechanisms, and it is essential to initiate appropriate treatment and improve the quality of life and survival of patients with this challenging disorder.
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Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review

TL;DR: High levels of evidence were found that AMs prevent lupus flares and increase long-term survival of patients with SLE; moderate evidence of protection against irreversible organ damage, thrombosis and bone mass loss and evidence supporting an effect on severe l upus activity, lipid levels and subclinical atherosclerosis was weak.
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Autoimmune diseases induced by TNF-targeted therapies: analysis of 233 cases.

TL;DR: The use of anti-TNF agents has been associated with an increasing number of cases of autoimmune diseases, principally cutaneous vasculitis, lupus-like syndrome, SLE, and interstitial lung disease.
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Immune-related adverse events of checkpoint inhibitors.

TL;DR: This Primer by Ramos-Casals and colleagues summarizes the epidemiology, mechanisms, diagnosis and treatment of immune-related adverse events and should be prescribed carefully to reduce the potential of short-term and long-term complications.