Showing papers in "Medicine in 2007"

TL;DR: The use of anti-TNF agents has been associated with an increasing number of cases of autoimmune diseases, principally cutaneous vasculitis, lupus-like syndrome, SLE, and interstitial lung disease.

TL;DR: Significant predictors for reaching a diagnosis included continuous fever; fever present for <180 days; elevated erythrocyte sedimentation rate, C-reactive protein, or lactate dehydrogenase; leukopenia; thrombocytosis; abnormal chest computed tomography (CT); and abnormal F-fluorodeoxyglucose positron emission tomographic (FDG-PET).

TL;DR: 2 stages of the disease, an initial severe febrile and eruptive polyarthritis, followed by disabling peripheral rheumatism that can persist for months are described, pointing out the possibility of transitory peripheral vascular disorders during the second stage and the occasional benefit of short-term corticosteroids.

TL;DR: Despite increased awareness and recognition and significant inroads into therapeutic frontiers, follow-up remains poor in developing countries and a return to previous level of functioning is not universal.

TL;DR: Systemic histoplasmosis should be suspected in patients who have lived in endemic areas with fever, bone marrow suppression, and elevated hepatic enzymes, particularly if they are immunocompromised, and Evaluation including a combination of Histoplasma serologic screening, urine antigen assay, and fungal culture will secure the diagnosis in most cases.

TL;DR: A high frequency of CNS and infectious complications was observed in this large series of patients with HHT-related PAVM and systematic screening for PAVM should be proposed, regardless of a patient's symptoms, familial history, or genetic considerations.

TL;DR: A progressive increase in the incidence of biopsy-proven GCA in northwestern Spain is confirmed, and it is suggested that there has been a change in the clinical spectrum of the disease.

TL;DR: Compared with pSS patients without PAH, patients with p SS-associated PAH had Raynaud phenomenon, cutaneous vasculitis, and interstitial lung disease significantly more frequently, suggesting that systemic vasculopathy, B-cell activation, and autoimmunity could play a role in the pathophysiology of pSS- associated PAH.

TL;DR: It is shown that antibiotics only improve survival if administered early in the course of anthrax infection, and vaccination that leads to the formation of antibodies to protective antigen is anti-inflammatory and beneficial in averting shock and improving survival.

TL;DR: A comprehensive, retrospective review of the English-language literature from 1986 to 2006, searching for reports describing cases of emphysematous cystitis, found 53 eligible cases, most of which were elderly women with diabetes mellitus, and found plain abdominal X-ray was highly sensitive, while abdominal computerized tomography was the most sensitive and specific diagnostic tool.

TL;DR: The universal PCR method has proved to be more sensitive, specific, and rapid than conventional culture methods, and should therefore be included as a new major Duke criterion for the diagnosis of IE.

TL;DR: Clinical findings suggestive of disseminated tuberculosis were miliary lung lesions, serum ferritin >1000 microg/L, infiltrative liver disease, and adjusted calcium >2.6 mmol/L; Simultaneously performing mycobacterial culture and histopathologic examination of bone marrow biopsy was more sensitive and faster than just performing myCobacterial blood culture in diagnosing disseminated TB.

TL;DR: Aseptic abscesses (AA) is an emergent and probably underrecognized entity that represents an apparently noninfectious inflammatory disorder involving neutrophils that responds to corticosteroid therapy.

TL;DR: Characteristics and outcomes of patients with CAP who were admitted to the ICU with those of patients managed on the ward were compared and patients with low Pneumonia Severity Index scores and low CURB-65 scores were admitted based on clinical judgment that appeared to supersede objective scoring.

TL;DR: The main finding was that the course of Susac syndrome is not self-limited as previously thought, since isolated retinal arteriolar involvement may occur as a very late manifestation.

TL;DR: Hormonal deficiencies associated with HP sarcoidosis frequently include hypogonadism (all patients) and to a lesser degree diabetes insipidus (7 of 9 patients).

TL;DR: It is suggested that a deficiency of thiamine or riboflavin may play a more pivotal role than previously recognized in the development of type B lactic acidosis associated with malignancy.

TL;DR: This cohort was characterized by frequent exposure to tobacco smoking and other inhaled agents, and a constantly favorable pulmonary outcome contrasting with frequent chronic renal failure.

TL;DR: Most patients presented with advanced disease at diagnosis (bone marrow involvement in 60% of cases) and the diversity of presenting manifestations of angioimmunoblastic T-cell lymphoma underlines the diversity in presenting manifestations.

TL;DR: Coexistence of multiple late sequelae was common in HSCT survivors, and the findings provide a basis for more effective patient counseling, optimal surveillance, and early intervention.

TL;DR: In patients with enterococcal endocarditis, nosocomial acquisition of infection is an important factor determining outcome; hence, major emphasis must be put on prevention as the incidence of bacteremia and the population of elderly people at risk continue to grow, the hazard of acquiring nosocomials enteringococcalEndocarditis may increase.

TL;DR: Evaluating the prevalence of Hypothenar hammer syndrome in patients with Raynaud phenomenon and the long-term outcome of patients with HHS found favorable outcomes in most patients after conservative measures were initiated found that surgery may be undertaken in the subgroup patients who exhibit improvement while receiving recurrence of HHS.

TL;DR: In this paper, the authors reviewed the cases of 11 patients with cryptococcosis and idiopathic CD4 lymphocytopenia referred to their institution in the previous 12 years, as well as 42 similar cases reported in the literature, to assess the characteristics of the infection in this population.

TL;DR: The clinical spectrum of pneumococcal disease and vaccine-breakthrough infections in HSCT recipients at the authors' cancer center in a retrospective analysis of all consecutive episodes of S. pneumoniae infection from 1989 through 2005 showed that patients receiving systemic corticosteroids had increased risk for bacteremic pneumonia.

TL;DR: Renal failure is a risk factor for CRSAB complications in patients with cancer, while patients with hematologic malignancies are prone to develop extravascular complications, and consideration should be given to extending the duration of therapy beyond 2 weeks.

TL;DR: Clinical features, pathogenesis, investigation and management of glomerulonephritis are reviewed, and strategies for investigation of proteinuria and haematuria, and for management of common forms of GN are presented.

TL;DR: In patients with WG, a strategy that limits or avoids CYC therapy produced a frequency of remission comparable to that achieved with conventional CYC protocols, excellent survival, and avoidance of long-term CYC toxicity.

TL;DR: 40 consecutive patients with renal granulomatoses, associated with pauci-immune crescentic glomerulonephritis in 2 patients and with vasculitis in another, seen in northeastern Paris hospitals between January 1991 and February 2004 are described.

TL;DR: The initial clinical and laboratory assessment of patients presenting with fever within 1 year after visiting a tropical or subtropical area can help in selecting appropriate investigations and empirical treatments for patients with imported fever.

TL;DR: The incidence of stones in children has increased by 19 % in the last 10 years, the age at first presentation is reducing, and the traditional male to female ratio of 3:1 is changing to a greater proportion of women.