Maoping Chu

TL;DR: The results indicate that the role of bFGF in myocardial I/R recovery is related to the inhibition of excessive autophagy and increased ubiquitinated protein clearance via the activation of PI3K/Akt/mTOR signaling.

TL;DR: In vivo, oral administration of PIC suppressed STZ-induced inflammation, oxidative stress hypertrophy, fibrosis and fibrosis in diabetic rats, thereby relieving cardiac dysfunction and improving both fibrosisand pathological changes in cardiac tissues of diabetic rats.

TL;DR: Coumarin induced a series of apoptotic features, including phosphatidylserine (PS) externalization, DNA fragmentation, and nuclear condensation, and was found to be low-toxic and effective in prolonging the survival of C. albicans-infected mice.

TL;DR: The increased miR‐223 in ECs could work as a novel endocrine genetic signal and participate in vascular injury of KD and may provide a novel mechanism and a new therapeutic target for vascular complication of KD.

TL;DR: Results showed that hucMSC‐exosomes could alleviate CVB3‐induced myocarditis via activating AMPK/mTOR‐mediated autophagy flux pathway to attenuate cardiomyocyte apoptosis, which will be benefit for MSC‐ exosome therapy of my Carditis in the future.