M
Marcel de Matas
Researcher at AstraZeneca
Publications - 37
Citations - 1522
Marcel de Matas is an academic researcher from AstraZeneca. The author has contributed to research in topics: Granulation & Targeted drug delivery. The author has an hindex of 22, co-authored 37 publications receiving 1154 citations. Previous affiliations of Marcel de Matas include University of Bradford.
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Biopolymer-based biomaterials for accelerated diabetic wound healing: A critical review.
Syed Ahmed Shah,Muhammad Sohail,Shahzeb Khan,Muhammad Usman Minhas,Marcel de Matas,Victoria Sikstone,Zahid Hussain,Mudassir Abbasi,Mubeen Kousar +8 more
TL;DR: The pathophysiological conditions associated with chronic and diabetic wounds are reviewed, highlighting potential biomaterials and polymers for establishing drug delivery systems, specifically for the treatment of diabetic wounds and the promotion of the associated mechanisms involved in advanced wound healing.
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Twin Screw Granulation – A Literature Review
Timothy Chan Seem,Neil A. Rowson,Andrew Ingram,Zhenyu Huang,Shen Yu,Marcel de Matas,Ian Gabbott,Gavin K. Reynolds +7 more
TL;DR: In this article, the authors present a review of the literature on twin screw granulation (TSG) and discuss the control of the geometry of the granulator over the formation of granules and mechanisms of granulation.
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Metamorphosis of caffeine hydrate and anhydrous caffeine
TL;DR: The phase stability, interconversion and physicochemical characterisation of caffeine (1,3,7trimethylpurine-2,6-dione) hydrate and anhydrous caffeine relate to the strength of the available hydrogen-bonds as mentioned in this paper.
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PEGylation: a promising strategy to overcome challenges to cancer-targeted nanomedicines: a review of challenges to clinical transition and promising resolution
Zahid Hussain,Shahzeb Khan,Muhammad Imran,Muhammad Sohail,Syed Wadood Ali Shah,Marcel de Matas +5 more
TL;DR: A comprehensive overview of the pharmaceutical advantages and therapeutic feasibility of PEGylation of nanocarriers in improving tumor-specific targetability, reversing drug resistance, and improving pharmacokinetic profile of drugs and anticancer efficacy is presented.
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The effect of zinc oxide and titanium dioxide nanoparticles in the Comet assay with UVA photoactivation of human sperm and lymphocytes
TL;DR: Sperm and lymphocytes responses were statistically significant at the highest concentration for both PI and SI samples, and photogenotoxic events in these cells in the absence of overt toxicity are suggested.