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Marcel de Matas

Researcher at AstraZeneca

Publications -  37
Citations -  1522

Marcel de Matas is an academic researcher from AstraZeneca. The author has contributed to research in topics: Granulation & Targeted drug delivery. The author has an hindex of 22, co-authored 37 publications receiving 1154 citations. Previous affiliations of Marcel de Matas include University of Bradford.

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Biopolymer-based biomaterials for accelerated diabetic wound healing: A critical review.

TL;DR: The pathophysiological conditions associated with chronic and diabetic wounds are reviewed, highlighting potential biomaterials and polymers for establishing drug delivery systems, specifically for the treatment of diabetic wounds and the promotion of the associated mechanisms involved in advanced wound healing.
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Twin Screw Granulation – A Literature Review

TL;DR: In this article, the authors present a review of the literature on twin screw granulation (TSG) and discuss the control of the geometry of the granulator over the formation of granules and mechanisms of granulation.
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Metamorphosis of caffeine hydrate and anhydrous caffeine

TL;DR: The phase stability, interconversion and physicochemical characterisation of caffeine (1,3,7trimethylpurine-2,6-dione) hydrate and anhydrous caffeine relate to the strength of the available hydrogen-bonds as mentioned in this paper.
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PEGylation: a promising strategy to overcome challenges to cancer-targeted nanomedicines: a review of challenges to clinical transition and promising resolution

TL;DR: A comprehensive overview of the pharmaceutical advantages and therapeutic feasibility of PEGylation of nanocarriers in improving tumor-specific targetability, reversing drug resistance, and improving pharmacokinetic profile of drugs and anticancer efficacy is presented.
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The effect of zinc oxide and titanium dioxide nanoparticles in the Comet assay with UVA photoactivation of human sperm and lymphocytes

TL;DR: Sperm and lymphocytes responses were statistically significant at the highest concentration for both PI and SI samples, and photogenotoxic events in these cells in the absence of overt toxicity are suggested.