M
Marcelo Ramalho-Ortigao
Researcher at Uniformed Services University of the Health Sciences
Publications - 50
Citations - 1338
Marcelo Ramalho-Ortigao is an academic researcher from Uniformed Services University of the Health Sciences. The author has contributed to research in topics: Leishmania major & Aedes aegypti. The author has an hindex of 20, co-authored 44 publications receiving 1147 citations. Previous affiliations of Marcelo Ramalho-Ortigao include Kansas State University & National Institutes of Health.
Papers
More filters
Journal ArticleDOI
A Role for Insect Galectins in Parasite Survival
Shaden Kamhawi,Marcelo Ramalho-Ortigao,Van My Pham,Sanjeev Kumar,Phillip G. Lawyer,Salvatore J. Turco,Carolina Barillas-Mury,David L. Sacks,Jesus G. Valenzuela +8 more
TL;DR: PpGalec, a tandem repeat galectin expressed in the midgut of the sandfly Phlebotomus papatasi, is used by Leishmania major as a receptor for mediating specific binding to the insect midGut, an event crucial for parasite survival.
Journal ArticleDOI
Transgenesis and paratransgenesis to control insect-borne diseases: current status and future challenges.
TL;DR: The current status of transgenesis and paratransgenesis is highlighted, pointing out advantages and constraints, and issues that need to be resolved are explored before the establishment of transGenesis andParatransGenesis as tools to prevent vector-borne diseases.
Journal ArticleDOI
Exploring the midgut transcriptome of Phlebotomus papatasi: comparative analysis of expression profiles of sugar-fed, blood-fed and Leishmania major -infected sandflies
Marcelo Ramalho-Ortigao,Marcelo Ramalho-Ortigao,Ryan C. Jochim,Ryan C. Jochim,Jennifer M. Anderson,Phillip G. Lawyer,Van-My Pham,Shaden Kamhawi,Jesus G. Valenzuela +8 more
TL;DR: The findings presented in this work suggest that the Leishmania parasite is modulating key enzymes or proteins in the gut of the sandfly that may be beneficial for its establishment and survival.
Journal ArticleDOI
Significance of bacteria in oviposition and larval development of the sand fly Lutzomyia longipalpis
TL;DR: The bacterial community in the sand fly larval habitat affects oviposition and larval development although bacteria are not essential for successful development of L. longipalpis.
Journal ArticleDOI
Transmission blocking vaccines to control insect-borne diseases: a review
TL;DR: In this review, many of the TBV strategies against insect-borne pathogens and their respective ramification with regards to the immune response of the vertebrate host are discussed.