M
Márcia Machado Marinho
Researcher at State University of Ceará
Publications - 91
Citations - 375
Márcia Machado Marinho is an academic researcher from State University of Ceará. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 6, co-authored 62 publications receiving 154 citations. Previous affiliations of Márcia Machado Marinho include Federal University of Ceará.
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Journal ArticleDOI
Antiviral activity on the Zika virus and larvicidal activity on the Aedes spp. of Lippia alba essential oil and β-caryophyllene
Antonio Carlos Nogueira Sobrinho,Selene Maia de Morais,Márcia Machado Marinho,Natália Vasconcelos de Souza,Danielle Malta Lima +4 more
TL;DR: Essential oil from L. alba and its major compound β-caryophyllene were examined for its antiviral activity against Zika virus in vitro and in silico and exhibited a greater antiviral effect in the assays of virucidal activity and post-treatment.
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Lectin purified from Lonchocarpus campestris seeds inhibits inflammatory nociception.
Alana de Freitas Pires,Alana de Freitas Pires,Mirna Marques Bezerra,Renata Morais Ferreira Amorim,Francisco Lucas Faustino do Nascimento,Márcia Machado Marinho,Raniere da Mata Moura,Mayara Torquato Lima Silva,Jorge Luis Almeida Correia,Benildo Sousa Cavada,Ana Maria Sampaio Assreuy,Kyria S. Nascimento +11 more
TL;DR: LCaL injected by intravenous route in mice showed antinociceptive activity in the behavioral tests of Formalin and Writhing, mainly via inhibition of inflammation.
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A novel N-acetyl-glucosamine lectin of Lonchocarpus araripensis attenuates acute cellular inflammation in mice.
Alana de Freitas Pires,Alana de Freitas Pires,Natália Velloso Fontenelle Camelo Rodrigues,Pedro Marcos Gomes Soares,Ronaldo A. Ribeiro,Karoline S. Aragão,Márcia Machado Marinho,Mayara Torquato Lima Silva,Benildo Sousa Cavada,Ana Maria Sampaio Assreuy +9 more
TL;DR: The novel N-acetyl-d-glucosamine-binding lectin isolated from L. araripensis seeds presents anti-inflammatory effect involving the lectin domain and the inhibition of 5-HT, BK, PGE2, NO, TNF-α and leukocyte rolling and adhesion.
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Antiparasitic effect of (−)-α-bisabolol against Trypanosoma cruzi Y strain forms
Ramon Róseo Paula Pessoa Bezerra de Menezes,Tiago Lima Sampaio,Danya Bandeira Lima,Paloma Leão Sousa,Isabella Evelyn Prado de Azevedo,Emanuel Paula Magalhães,Louise Donadello Tessarolo,Márcia Machado Marinho,Ricardo Pires dos Santos,Alice Maria Costa Martins +9 more
TL;DR: The results demonstrate that BIS causes cell death in Trypanosoma cruzi Y strain forms, with the involvement of apoptosis and oxidative stress and enzymatic inhibition.
Journal ArticleDOI
Structural characterization, DFT calculations, ADMET studies, antibiotic potentiating activity, evaluation of efflux pump inhibition and molecular docking of chalcone (E)-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one
Jayze da Cunha Xavier,Francisco Wagner de Queiroz Almeida-Neto,Priscila Teixeira da Silva,Amanda Pereira de Sousa,Emmanuel Silva Marinho,Márcia Machado Marinho,Janaína Esmeraldo Rocha,Priscila R. Freitas,Ana Carolina Justino de Araújo,Thiago Santiago Freitas,Carlos Emídio Sampaio Nogueira,Pedro de Lima-Neto,Paulo Nogueira Bandeira,Alexandre Magno Rodrigues Teixeira,Henrique Douglas Melo Coutinho,Hélcio Silva dos Santos +15 more
TL;DR: In this paper, the electronic properties of the chalcone, (E)-1-(2-hydroxy)-3,4,6-trimethoxyphenyl)-3-(4-methoxymhenyl) prop-2-en-1-one synthesized by Claisen-Schmidt condensation reaction were performed.