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Marcin J. Mizianty
Researcher at University of Alberta
Publications - 36
Citations - 3033
Marcin J. Mizianty is an academic researcher from University of Alberta. The author has contributed to research in topics: Proteome & Intrinsically disordered proteins. The author has an hindex of 26, co-authored 36 publications receiving 2578 citations. Previous affiliations of Marcin J. Mizianty include University of South Florida.
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Journal ArticleDOI
D2P2: database of disordered protein predictions
Matt E. Oates,Pedro Romero,Takashi Ishida,Mohamed Ghalwash,Marcin J. Mizianty,Bin Xue,Zsuzsanna Dosztányi,Vladimir N. Uversky,Zoran Obradovic,Lukasz Kurgan,A. Keith Dunker,Julian Gough +11 more
TL;DR: The Database of Disordered Protein Prediction (D2P2) will increase the understanding of the interplay between disorder and structure, the genomic distribution of disorder, and its evolutionary history.
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MoRFpred, a computational tool for sequence-based prediction and characterization of short disorder-to-order transitioning binding regions in proteins
Fatemeh Miri Disfani,Wei-Lun Hsu,Marcin J. Mizianty,Christopher J. Oldfield,Bin Xue,A. Keith Dunker,Vladimir N. Uversky,Lukasz Kurgan +7 more
TL;DR: A new MoRF predictor, MoRFpred, is introduced, which identifies all MoRF types (α, β, coil and complex) and identifies a few sequence-derived hallmarks of MoRFs, characterized by dips in the disorder predictions and higher hydrophobicity and stability when compared to adjacent residues.
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Exceptionally abundant exceptions: comprehensive characterization of intrinsic disorder in all domains of life
Zhenling Peng,Jing Yan,Xiao Fan,Marcin J. Mizianty,Bin Xue,Kui Wang,Gang Hu,Vladimir N. Uversky,Vladimir N. Uversky,Lukasz Kurgan +9 more
TL;DR: This work comprehensively characterized intrinsic disorder at proteomic and protein levels from all significant perspectives, including abundance, cellular localization, functional roles, evolution, and impact on structural coverage, and shows that intrinsic disorder is more abundant and has a unique profile in eukaryotes.
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Improved sequence-based prediction of disordered regions with multilayer fusion of multiple information sources
Marcin J. Mizianty,Wojciech Stach,Ke Chen,Kanaka Durga Kedarisetti,Fatemeh Miri Disfani,Lukasz Kurgan +5 more
TL;DR: A novel method, named MFDp (Multilayered Fusion-based Disorder predictor), that aims to improve over the current disorder predictors and consistently and significantly outperforms the other methods based on the MCC index.
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A creature with a hundred waggly tails: intrinsically disordered proteins in the ribosome.
Zhenling Peng,Christopher J. Oldfield,Bin Xue,Marcin J. Mizianty,A. Keith Dunker,Lukasz Kurgan,Vladimir N. Uversky,Vladimir N. Uversky +7 more
TL;DR: In this paper, the authors present the results of comprehensive bioinformatics analyses of the abundance and roles of intrinsic disorder in 3,411 ribosomal proteins from 32 species.