M
Marcin Kruszewski
Researcher at Translational Research Institute
Publications - 208
Citations - 7012
Marcin Kruszewski is an academic researcher from Translational Research Institute. The author has contributed to research in topics: Comet assay & DNA damage. The author has an hindex of 38, co-authored 193 publications receiving 5919 citations. Previous affiliations of Marcin Kruszewski include Information Technology University & University of Dundee.
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Journal ArticleDOI
The comet assay: topical issues
Andrew Collins,Amaia Azqueta Oscoz,Gunnar Brunborg,Isabel Gaivão,Isabel Gaivão,Lisa Giovannelli,Marcin Kruszewski,Catherine C. Smith,Rudolf Stetina +8 more
TL;DR: The comet assay is a versatile and sensitive method for measuring single- and double-strand breaks in DNA, and by including lesion-specific enzymes in the assay, its range and sensitivity are greatly increased, but it is important to bear in mind that their specificity is not absolute.
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Labile iron pool: the main determinant of cellular response to oxidative stress.
TL;DR: The critical factor appears to be the availability and abundance of cellular labile iron pool (LIP) that constitutes a crossroad of metabolic pathways of iron-containing compounds and is midway between the cellular need of iron, its uptake and storage.
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Cytotoxic and genotoxic effects of silver nanoparticles in testicular cells.
Nana Asare,Christine Instanes,Wiggo J. Sandberg,Magne Refsnes,Per E. Schwarze,Marcin Kruszewski,Gunnar Brunborg +6 more
TL;DR: Results suggest that silver nano- and submicron-particles (AgNPs) are more cytotoxic and cytostatic compared to TiO(2)-NPs, causing apoptosis, necrosis and decreased proliferation in a concentration- and time-dependent manner.
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The effect of agglomeration state of silver and titanium dioxide nanoparticles on cellular response of HepG2, A549 and THP-1 cells.
Anna Lankoff,Wiggo J. Sandberg,Aneta Wegierek-Ciuk,Halina Lisowska,Magne Refsnes,Bożena Sartowska,Per E. Schwarze,Sylwia Męczyńska-Wielgosz,Maria Wojewódzka,Marcin Kruszewski +9 more
TL;DR: The findings suggest that particle features such as size and agglomeration status as well as the type of cells may contribute to nanoparticles biological impact.
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Time-dependent biodistribution and excretion of silver nanoparticles in male Wistar rats.
Katarzyna Dziendzikowska,Joanna Gromadzka-Ostrowska,Anna Lankoff,Michał Oczkowski,Agata Krawczyńska,J. Chwastowska,M. Sadowska-Bratek,E. Chajduk,Maria Wojewódzka,Maria Dusinska,Marcin Kruszewski +10 more
TL;DR: Using inductively coupled plasma‐mass spectrometry (ICP‐MS) and transmission electron microscopy (TEM) it was observed that AgNPs translocated from the blood to the main organs and the concentration of silver in tissues was significantly higher in rats treated with 20 nm AgNBP as compared with 200 nm AgNPS.