Marco Vilela

TL;DR: By reversibly sequestering proteins at mitochondria, LOVTRAP precisely modulated the proteins' access to the cell edge, demonstrating a naturally occurring 3-mHz cell-edge oscillation driven by interactions of Vav2, Rac1, and PI3K proteins.

TL;DR: The proposed method of eigenvector optimization constitutes an advancement over S-system parameter identification from time series using a recent method called Alternating Regression and overcomes convergence issues encountered in alternate regression by identifying nonlinear constraints that restrict the search space to computationally feasible solutions.

TL;DR: The Whittaker's smoother is reformulated within the context of information theory and extended by the development of adaptive signal segmentation to account for heterogeneous noise structures and constitutes a rather general tool for the reverse engineering of mechanistic model descriptions from multivariate experimental time series.

TL;DR: In this paper, the authors demonstrate the first human use of a wireless broadband brain-computer interface (iBCI) in the presence of tetraplegia and demonstrate on-screen item selection tasks to assess iBCI enabled cursor control.

TL;DR: A model in which surges in ERK activity induced by extracellular cues enhance Arp2/3-mediated actin polymerization to generate protrusion power phases with enough force to counteract increasing membrane tension and to promote sustained motility is supported.