M
Marcus Bandstein
Researcher at Uppsala University
Publications - 11
Citations - 223
Marcus Bandstein is an academic researcher from Uppsala University. The author has contributed to research in topics: DNA methylation & Single-nucleotide polymorphism. The author has an hindex of 8, co-authored 11 publications receiving 167 citations.
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Journal ArticleDOI
An obesity-associated risk allele within the FTO gene affects human brain activity for areas important for emotion, impulse control and reward in response to food images.
Lyle Wiemerslage,Emil K. Nilsson,Linda Solstrand Dahlberg,Fia Ence-Eriksson,Sandra Castillo,Anna L. Larsen,Simon B. A. Bylund,Pleunie S. Hogenkamp,Gaia Olivo,Marcus Bandstein,Olga E. Titova,Elna-Marie Larsson,Christian Benedict,Samantha J. Brooks,Helgi B. Schiöth +14 more
TL;DR: The results suggest that the two genotypes are associated with differential neural processing of food images, which may influence weight status through diminished impulse control and reward processing.
Journal ArticleDOI
A Genetic Risk Score Is Associated with Weight Loss Following Roux-en Y Gastric Bypass Surgery
Marcus Bandstein,Sarah Voisin,Emil K. Nilsson,Bernd Schultes,Barbara Ernst,Martin Thurnheer,Christian Benedict,Jessica Mwinyi,Helgi B. Schiöth +8 more
TL;DR: Two GRSs composed of BMI and WHR-associated SNPs with significant impact on weight loss after RYGB surgery are identified using random forest analysis as a SNP selection tool and may be useful to pre-surgically evaluate the risks for patients undergoing RyGB surgery.
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Resting-State Brain and the FTO Obesity Risk Allele: Default Mode, Sensorimotor, and Salience Network Connectivity Underlying Different Somatosensory Integration and Reward Processing between Genotypes.
Gaia Olivo,Lyle Wiemerslage,Emil K. Nilsson,Linda Solstrand Dahlberg,Anna L. Larsen,Marcela Olaya Búcaro,Veronica P. Gustafsson,Olga E. Titova,Marcus Bandstein,Elna-Marie Larsson,Christian Benedict,Samantha J. Brooks,Helgi B. Schiöth +12 more
TL;DR: It is suggested that neural connectivity patterns influence the sensitivity toward punishment and reward more closely in the AA carriers, predisposing them to developing obesity.
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A methylome-wide mQTL analysis reveals associations of methylation sites with GAD1 and HDAC3 SNPs and a general psychiatric risk score.
Diana-Maria Ciuculete,Adrian Boström,Sarah Voisin,H. Philipps,Olga E. Titova,Marcus Bandstein,Lamia Nikontovic,Michael Williams,Jessica Mwinyi,Helgi B. Schiöth +9 more
TL;DR: Results show how distinct SNPs linked with psychiatric diseases are associated with epigenetic shifts with relevance for gene expression, giving a novel insight on how genetic variants may modulate risks for the development of psychiatric diseases.
Journal ArticleDOI
Postprandial alterations in whole-blood DNA methylation are mediated by changes in white blood cell composition
Mathias Rask-Andersen,Nathalie Bringeland,Emil K. Nilsson,Marcus Bandstein,Marcela Olaya Búcaro,Heike Vogel,Annette Schürmann,Pleunie S. Hogenkamp,Christian Benedict,Helgi B. Schiöth +9 more
TL;DR: These results have major methodologic implications for genome-wide methylation studies because they highlight the strong underlying effects of changes in leukocyte fractions on CpG methylation patterns as well as the potential importance of meal-standardized sampling procedures for future investigations when alterations in white blood cell fractions are unavailable.