M
Marcus Koch
Researcher at Leibniz Association
Publications - 98
Citations - 1470
Marcus Koch is an academic researcher from Leibniz Association. The author has contributed to research in topics: Medicine & Nanoparticle. The author has an hindex of 18, co-authored 84 publications receiving 920 citations. Previous affiliations of Marcus Koch include Saarland University.
Papers
More filters
Journal ArticleDOI
Differential cell reaction upon Toll-like receptor 4 and 9 activation in human alveolar and lung interstitial macrophages
Jessica Hoppstädter,Britta Diesel,Robert Zarbock,Tanja Breinig,Dominik Monz,Marcus Koch,Andreas Meyerhans,Andreas Meyerhans,Ludwig Gortner,Claus-Michael Lehr,Hanno Huwer,Alexandra K. Kiemer +11 more
TL;DR: IM were found to be smaller and morphologically more heterogeneous than AM, whereas phagocytic activity was similar in both cell types, which should be taken into consideration in future studies on the role of human lung MΦ in the inflammatory response.
Journal ArticleDOI
Lipid droplets as a novel cargo of tunnelling nanotubes in endothelial cells
TL;DR: The results provide the first demonstration of lipid droplets as a cargo of TNTs and thereby open a new field in intercellular communication research.
Journal ArticleDOI
Biocompatible bacteria-derived vesicles show inherent antimicrobial activity.
Eilien Schulz,Adriely Goes,Ronald Garcia,Fabian Panter,Marcus Koch,Rolf Müller,Kathrin Fuhrmann,Gregor Fuhrmann +7 more
TL;DR: The characterisation of naturally derived outer membrane vesicles (OMVs) as biocompatible and inherently antibiotic drug carriers and the presence of cystobactamids in OMVs may serve as an important basis for further evaluation of OMVs derived from myxobacteria as novel therapeutic delivery systems against bacterial infections.
Journal ArticleDOI
Streptococcal Extracellular Membrane Vesicles Are Rapidly Internalized by Immune Cells and Alter Their Cytokine Release.
TL;DR: A better understanding is provided of gram-positive streptococcal MVs and their potential to elicit a protective immune response and they could offer an innovative avenue for safe and effective cell-free vaccination against pneumococcal infections.
Journal ArticleDOI
A hydrophobic starch polymer for nanoparticle-mediated delivery of docetaxel.
Prajakta Dandekar,Ratnesh Jain,Thomas Stauner,Brigitta Loretz,Marcus Koch,Gerhard Wenz,Claus-Michael Lehr +6 more
TL;DR: The application of this polymer for formulating nanoparticles of docetaxel, an anti-cancer agent effective against numerous types of cancers but possessing intrinsic formulation difficulties is described.