Marcus Koch

TL;DR: A simple fast, practical and effective method for the replication of the complex venation patterns of natural leaves into PDMS with accuracy down to a lateral size of 500 nm, making this method especially attractive for mimicking biological structures for in vitro assays.

TL;DR: In this article, surface morphometry combined with single-cell force spectroscopy was performed on surfaces with irregular topographies on the nano-scale to quantify surface topography and bacterial adhesion.

TL;DR: Treatment of HEp‐2 and Caco‐2 cells infected with Salmonella enterica using colistin‐containing, Eap‐functionalized liposomes resulted in a significant reduction of intracellular bacteria, which indicates that such bio‐invasive carriers are able to facilitate intrACEllular delivery of colistsin, as necessary for intracesllular anti‐infective activity.

TL;DR: Cellular uptake studies by confocal laser scanning microscopy revealed a higher cellular uptake of ptPVA stabilized nanoparticles thus confirming the proposed hypothesis of higher protein adsorption being responsible for higher cellular internalization.

TL;DR: Self‐assembling nanoparticles of a newly synthesized squalenyl hydrogen sulfate (SqNPs) showed improved biofilm penetration and enhanced efficacy in relevant biological barriers, leading to complete eradication of PA biofilms at circa 16‐fold lower Tob concentration than Tob alone.