C
Christian Jüngst
Researcher at University of Cologne
Publications - 30
Citations - 1614
Christian Jüngst is an academic researcher from University of Cologne. The author has contributed to research in topics: Lipid droplet & Angiogenesis. The author has an hindex of 17, co-authored 28 publications receiving 1249 citations. Previous affiliations of Christian Jüngst include University of Konstanz.
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Journal ArticleDOI
A novel multiplex bead-based platform highlights the diversity of extracellular vesicles
Nina Koliha,Yvonne Wiencek,Ute Heider,Christian Jüngst,Nikolay Kladt,Susanne Krauthäuser,Ian C.D. Johnston,Andreas Bosio,Astrid Schauss,Stefan Wild +9 more
TL;DR: A novel multiplex bead-based platform to investigate up to 39 different surface markers in one sample and show for the first time that NK cell–derived EVs and platelet-derived EVs are devoid of CD9 or CD81, respectively, and that EVs isolated from activated B cells comprise different EV subpopulations.
Journal ArticleDOI
Two‐Color Glycan Labeling of Live Cells by a Combination of Diels–Alder and Click Chemistry
Andrea Niederwieser,Anne-Katrin Späte,Long Duc Nguyen,Christian Jüngst,Werner Reutter,Valentin Wittmann +5 more
TL;DR: This work shows that ManNAc derivatives containing a terminal alkene in the acyl side chain are metabolically incorporated into cell-surface sialic acids and can subsequently be labeled by the DARinv, and identifies monosubstituted (terminal) alkenes as a new class of chemical reporters.
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Remodeling of Lipid Droplets during Lipolysis and Growth in Adipocytes
Margret Paar,Christian Jüngst,Noemi A. Steiner,Christoph Magnes,Frank Sinner,Dagmar Kolb,Achim Lass,Robert Zimmermann,Andreas Zumbusch,Sepp D. Kohlwein,Heimo Wolinski +10 more
TL;DR: These data indicate that LD growth is a highly regulated process leading to the heterogeneous LD size distribution within and between individual cells, and propose that formation of large LDs requires a yet uncharacterized protein machinery mediating LD interaction and lipid transfer.
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E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning
Matthias Rübsam,Aaron F. Mertz,Akiharu Kubo,Susanna Marg,Christian Jüngst,Gladiola Goranci-Buzhala,Astrid Schauss,Valerie Horsley,Eric R. Dufresne,Markus Moser,Wolfgang H. Ziegler,Masayuki Amagai,Sara A. Wickström,Carien M. Niessen +13 more
TL;DR: An E-cadherin-dependent mechanical circuit that integrates adhesion, contractile forces and biochemical signaling to drive the polarized organization of junctional tension necessary to build an in vivo epithelial barrier is identified.
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The ciliary membrane‐associated proteome reveals actin‐binding proteins as key components of cilia
Priyanka Kohli,Martin Höhne,Christian Jüngst,Sabine Bertsch,Lena K. Ebert,Astrid Schauss,Thomas Benzing,Markus M. Rinschen,Bernhard Schermer +8 more
TL;DR: A novel approach is presented to investigate dynamics of the ciliary membrane proteome in mammalian cells and identify actin‐binding proteins as mechanosensitive components of cilia that might have important functions in cilia membrane dynamics.