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Marcus Koch

Researcher at Leibniz Association

Publications -  98
Citations -  1470

Marcus Koch is an academic researcher from Leibniz Association. The author has contributed to research in topics: Medicine & Nanoparticle. The author has an hindex of 18, co-authored 84 publications receiving 920 citations. Previous affiliations of Marcus Koch include Saarland University.

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Differential cell reaction upon Toll-like receptor 4 and 9 activation in human alveolar and lung interstitial macrophages

TL;DR: IM were found to be smaller and morphologically more heterogeneous than AM, whereas phagocytic activity was similar in both cell types, which should be taken into consideration in future studies on the role of human lung MΦ in the inflammatory response.
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Lipid droplets as a novel cargo of tunnelling nanotubes in endothelial cells

TL;DR: The results provide the first demonstration of lipid droplets as a cargo of TNTs and thereby open a new field in intercellular communication research.
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Biocompatible bacteria-derived vesicles show inherent antimicrobial activity.

TL;DR: The characterisation of naturally derived outer membrane vesicles (OMVs) as biocompatible and inherently antibiotic drug carriers and the presence of cystobactamids in OMVs may serve as an important basis for further evaluation of OMVs derived from myxobacteria as novel therapeutic delivery systems against bacterial infections.
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Streptococcal Extracellular Membrane Vesicles Are Rapidly Internalized by Immune Cells and Alter Their Cytokine Release.

TL;DR: A better understanding is provided of gram-positive streptococcal MVs and their potential to elicit a protective immune response and they could offer an innovative avenue for safe and effective cell-free vaccination against pneumococcal infections.
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A hydrophobic starch polymer for nanoparticle-mediated delivery of docetaxel.

TL;DR: The application of this polymer for formulating nanoparticles of docetaxel, an anti-cancer agent effective against numerous types of cancers but possessing intrinsic formulation difficulties is described.