M
Margaret Warner
Researcher at University of Houston
Publications - 117
Citations - 13966
Margaret Warner is an academic researcher from University of Houston. The author has contributed to research in topics: Estrogen receptor & Estrogen receptor beta. The author has an hindex of 51, co-authored 113 publications receiving 13006 citations. Previous affiliations of Margaret Warner include Houston Methodist Hospital & Karolinska Institutet.
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Journal ArticleDOI
Mechanisms of Estrogen Action
Stefan Nilsson,Sari Mäkelä,Eckardt Treuter,Michel Tujague,Jane S. Thomsen,Göran Andersson,Eva Enmark,Katarina Pettersson,Margaret Warner,Jan-Åke Gustafsson +9 more
TL;DR: The role of estrogen receptors in physiology and pathology has been investigated in the past decade and it was found that there was not one but two distinct and functional estrogen receptors, now called ERα and ERβ.
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Generation and reproductive phenotypes of mice lacking estrogen receptor β
John H. Krege,Jeffrey B. Hodgin,John F. Couse,Eva Enmark,Margaret Warner,Joel F. Mahler,Madhabananda Sar,Kenneth S. Korach,Jan-Åke Gustafsson,Oliver Smithies +9 more
TL;DR: The generation of mice lacking estrogen receptor beta (ERbeta -/-) is described by insertion of a neomycin resistance gene into exon 3 of the coding gene by using homologous recombination in embryonic stem cells to determine the role of ERbeta in bone and cardiovascular homeostasis.
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Estrogen Receptors: How Do They Signal and What Are Their Targets
Nina Heldring,Ashley C. W. Pike,Sandra Andersson,Jason Matthews,Guojun Cheng,Johan Hartman,Michel Tujague,Anders Ström,Eckardt Treuter,Margaret Warner,Jan-Åke Gustafsson +10 more
TL;DR: This review focuses on several of the interesting recent discoveries concerning estrogen receptors, on estrogen as a morphogen, and on the molecular mechanisms of anti-estrogen signaling.
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Estrogen receptor (ER) β, a modulator of ERα in the uterus
Zhang Weihua,Shigehira Saji,Sirpa Mäkinen,Guojun Cheng,Elwood V. Jensen,Margaret Warner,Jan-Åke Gustafsson +6 more
TL;DR: In this paper, the role of ERβ in modulation of the effects of estrogens on the uterus was explored in BERKO female mice, and the effect of 17β-estradiol (E2) treatment on the stroma was investigated.
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A role for estrogen receptor β in the regulation of growth of the ventral prostate
Zhang Weihua,Sari Mäkelä,Sari Mäkelä,Leif C. Andersson,Leif C. Andersson,Saija Salmi,Shigehira Saji,Jeanette I Webster,Elwood V. Jensen,Stefan K. Nilsson,Margaret Warner,Jan-Ake Gustafsson +11 more
TL;DR: Findings suggest that ligands specific for ERβ may be useful in the prevention and/or clinical management of prostatic hyperplasia and neoplasia.