E
Eckardt Treuter
Researcher at Karolinska Institutet
Publications - 78
Citations - 8852
Eckardt Treuter is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Nuclear receptor & Corepressor. The author has an hindex of 42, co-authored 73 publications receiving 8263 citations.
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Journal ArticleDOI
Mechanisms of Estrogen Action
Stefan Nilsson,Sari Mäkelä,Eckardt Treuter,Michel Tujague,Jane S. Thomsen,Göran Andersson,Eva Enmark,Katarina Pettersson,Margaret Warner,Jan-Åke Gustafsson +9 more
TL;DR: The role of estrogen receptors in physiology and pathology has been investigated in the past decade and it was found that there was not one but two distinct and functional estrogen receptors, now called ERα and ERβ.
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Estrogen Receptors: How Do They Signal and What Are Their Targets
Nina Heldring,Ashley C. W. Pike,Sandra Andersson,Jason Matthews,Guojun Cheng,Johan Hartman,Michel Tujague,Anders Ström,Eckardt Treuter,Margaret Warner,Jan-Åke Gustafsson +10 more
TL;DR: This review focuses on several of the interesting recent discoveries concerning estrogen receptors, on estrogen as a morphogen, and on the molecular mechanisms of anti-estrogen signaling.
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Activation functions 1 and 2 of nuclear receptors: molecular strategies for transcriptional activation.
TL;DR: This review summarizes and discusses current knowledge regarding the molecular mechanisms of AF-1- and AF-2-mediated gene activation, focusing on AF- 1 andAF-2 conformation and coactivator binding.
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Liver X receptor biology and pharmacology: new pathways, challenges and opportunities
TL;DR: The current status of the understanding of the LXR biology and pharmacology is discussed, with an emphasis on the molecular aspects of LXR signaling that constitute the potential of LXRs as drug targets.
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A Regulatory Role for RIP140 in Nuclear Receptor Activation
TL;DR: This work proposes a model in which RIP140 indirectly regulates nuclear receptor AF-2 activity by competition for coactivators such as SRC-1, and provides important evidence that the in vitro binding of RIP140 and S RC-1 to nuclear receptors is competitive.