M
Maria Auxiliadora Coelho Kaplan
Researcher at Federal University of Rio de Janeiro
Publications - 202
Citations - 4256
Maria Auxiliadora Coelho Kaplan is an academic researcher from Federal University of Rio de Janeiro. The author has contributed to research in topics: Essential oil & Piperaceae. The author has an hindex of 31, co-authored 200 publications receiving 3887 citations. Previous affiliations of Maria Auxiliadora Coelho Kaplan include University of São Paulo & Bar-Ilan University.
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Journal ArticleDOI
Selective Effect of 2′,6′-Dihydroxy-4′-Methoxychalcone Isolated from Piper aduncum on Leishmania amazonensis
Eduardo Caio Torres-Santos,Davyson de Lima Moreira,Maria Auxiliadora Coelho Kaplan,Maria de Nazareth Leal de Meirelles,Bartira Rossi-Bergmann +4 more
TL;DR: Observations suggest that DMC is selectively toxic to the parasites, and its simple structure may well enable it to serve as a new lead compound for the synthesis of novel antileishmanial drugs.
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Antibacterial Phloroglucinols and Flavonoids from Hypericum brasiliense
Leandro Rocha,Andrew Marston,Olivier Potterat,Maria Auxiliadora Coelho Kaplan,Helen Stoeckli-Evans,Kurt Hostettmann +5 more
TL;DR: Four phloroglucinols have been isolated from a petrol extract of the leaves and flowers of Hypericum brasiliense and were antibacterial against Bacillus subtilis in a TLC bioautographic assay.
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Antimicrobial activity in vitro of plumbagin isolated from Plumbago species.
Selma Ribeiro de Paiva,Maria Raquel Figueiredo,Tânia Verônica Aragão,Maria Auxiliadora Coelho Kaplan +3 more
TL;DR: The naphthoquinone plumbagin is suggested as a promising antimicrobial agent against bacteria and yeast.
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Pentacyclic triterpenes from Chrysobalanaceae species: cytotoxicity on multidrug resistant and sensitive leukemia cell lines
Janaina Fernandes,Rachel Oliveira Castilho,Mariana Rangel da Costa,Karen Wagner-Souza,Maria Auxiliadora Coelho Kaplan,Cerli Rocha Gattass +5 more
TL;DR: These triterpenoids inhibited the growth and induced apoptosis of K562, an erythroleukemia cell line and inhibited the proliferation of Lucena 1, a vincristine-resistant derivative of K582 that displays several multidrug resistance (MDR) characteristics.
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Anthelmintic activity of the latex of Ficus species.
Alziro de Amorin,Helcio Resende Borba,Jorge Pedro Pereira Carauta,Daíse Lopes,Maria Auxiliadora Coelho Kaplan +4 more
TL;DR: The observed high acute toxicity with hemorrhagic enteritis, in addition to a weak anthelmintic efficacy, do not recommend the use of these lattices in traditional medicine.