Maria Eliana Lai

TL;DR: Hepatocellular carcinoma (HCC) frequently complicates hepatic cirrhosis secondary to viral infection or iron overload, and patients affected by thalassaemia syndromes have a theoretically high risk of developing the tumour.

TL;DR: The results suggest that deferasirox had a positive impact on patients' daily lives, and patient-reported satisfaction and convenience were significantly higher for the once-daily, oral ICT defer asirox than for DFO infusions.

TL;DR: Assessment of T2* value distribution in the left ventricle and a correction procedure to compensate for artefactual variations in segmental analysis confirmed that susceptibility artefacts are additive in nature and become negligible for high levels of iron overload.

TL;DR: A multicenter cross-sectional study of 1309 Italian β-thalassemia patients with tricuspid-valve regurgitant jet velocity ≥ 32 m/s on transthoracic echocardiography further underwent right heart catheterization to confirm the diagnosis of pulmonary arterial hypertension.

TL;DR: The risk of developing hepatocellular carcinoma (HCC) in patients with thalassaemia is increased by transfusion‐transmitted infections and haemosiderosis and Ultrasonography is recommended every 6 months to enable early diagnosis of HCC, which is crucial to decrease mortality.