M
María Gabriela Ortega
Researcher at National University of Cordoba
Publications - 39
Citations - 729
María Gabriela Ortega is an academic researcher from National University of Cordoba. The author has contributed to research in topics: Dalea & Superoxide dismutase. The author has an hindex of 16, co-authored 37 publications receiving 600 citations. Previous affiliations of María Gabriela Ortega include National Scientific and Technical Research Council.
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Inhibitory effect of quercetin on matrix metalloproteinase 9 activity Molecular mechanism and structure-activity relationship of the flavonoid-enzyme interaction
Alejandra C. Saragusti,María Gabriela Ortega,María Gabriela Ortega,José Luis Cabrera,José Luis Cabrera,Darío A. Estrin,Marcelo A. Martí,Marcelo A. Martí,Marcelo A. Martí,Gustavo A. Chiabrando,Gustavo A. Chiabrando +10 more
TL;DR: The data constitute the first evidence about the quercetin and MMP-9 interaction, suggesting a mechanism to explain the inhibitory effect of the flavonoid on the enzymatic activity of M MP-9, which provides an additional molecular target for the cardioprotective activity of quercETin.
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Anticholinesterase activity in an alkaloid extract of Huperzia saururus
TL;DR: The anticholinesterase activity in vitro of the alkaloid extract is studied using erythrocyte membranes and human serum as sources of acetylcholines terase and pseudocholinestersterase, showing a selectivity of the extract for the true acetylCholinesTERase.
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Investigation of the in vitro and ex vivo acetylcholinesterase and antioxidant activities of traditionally used Lycopodium species from South America on alkaloid extracts.
Eduardo Luis Konrath,Bruna Medeiros Neves,Paula Lunardi,Carolina dos Santos Passos,André Simões-Pires,María Gabriela Ortega,Carlos Alberto Gonçalves,José Luis Cabrera,José Cláudio Fonseca Moreira,Amélia T. Henriques +9 more
TL;DR: This study showed that the biological properties of the folk medicinal plants LyCopodium clavatum and Lycopodium thyoides include AChE inhibitory activity and antioxidant effects, two possible mechanisms of action in Alzheimer's related processes.
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Antifungal activity of a prenylated flavonoid from Dalea elegans against Candida albicans biofilms.
Mariana Andrea Peralta,María Angel da Silva,María Gabriela Ortega,José Luis Cabrera,María Gabriela Paraje +4 more
TL;DR: The data suggest that 8PP may be useful for the treatment of biofilm-related Candida infections, through an accumulation of endogenous ROS and RNI that can induce an adaptive response based on a coordinated increase in antioxidant defenses.
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Xanthine oxidase inhibitory activity of natural and hemisynthetic flavonoids from Gardenia oudiepe (Rubiaceae) in vitro and molecular docking studies.
María Daniela Santi,M. Paulino Zunini,Brenda Vera,Chouaha Bouzidi,V. Dumontet,A. Abin-Carriquiry,Raphaël Grougnet,María Gabriela Ortega,María Gabriela Ortega +8 more
TL;DR: A series of polymethoxyflavones isolated and hemisynthesized from the bud exudates of Gardenia oudiepe has been evaluated for in-vitro XO inhibitory activity and promising results are suggested, suggest the use of these compounds as potential leads for the design and development of novel XO inhibitors.