M
María J. Bustos
Researcher at Spanish National Research Council
Publications - 22
Citations - 654
María J. Bustos is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Virus & African swine fever virus. The author has an hindex of 11, co-authored 21 publications receiving 462 citations. Previous affiliations of María J. Bustos include Autonomous University of Madrid.
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Journal ArticleDOI
BA71ΔCD2: a New Recombinant Live Attenuated African Swine Fever Virus with Cross-Protective Capabilities
Paula L. Monteagudo,Anna Lacasta,Elisabeth Lopez,Laia Bosch,Javier Collado,Sonia Pina-Pedrero,Florencia Correa-Fiz,Francesc Accensi,Maria Jesus Navas,Enric Vidal,María J. Bustos,Javier M. Rodríguez,Andreas Gallei,Veljko Nikolin,María L. Salas,Fernando Rodriguez +15 more
TL;DR: Inoculation of pigs with the deletion mutant virus BA71ΔCD2 protected pigs not only against experimental challenge with BA71, the virulent parental strain, but also against heterologous viruses, including Georgia 2007/1, the genotype II strain of ASFV currently circulating in Eastern Europe.
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The C-type lectin homologue gene (EP153R) of African swine fever virus inhibits apoptosis both in virus infection and in heterologous expression.
Carolina Hurtado,Aitor G. Granja,María J. Bustos,Maria L. Nogal,Gonzalo González de Buitrago,Virginia G. de Yébenes,María L. Salas,Yolanda Revilla,Angel L. Carrascosa +8 more
TL;DR: The presence of gene EP153R resulted in a reduction of the transactivating activity of the cellular protein p53 in Vero cell cultures in which apoptosis was induced by virus infection or staurosporine treatment, to be the first description of a viral C-type lectin with anti-apoptotic properties.
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African swine fever virus EP153R open reading frame encodes a glycoprotein involved in the hemadsorption of infected cells.
TL;DR: The gene EP153R is needed to induce and/or maintain the interaction between the viral CD2 homolog and its corresponding cell receptor, and abrogated the hemadsorption phenomenon induced in ASF virus-infected cells.
Journal ArticleDOI
Antiviral activity of lauryl gallate against animal viruses
Carolina Hurtado,María J. Bustos,Prado Sabina,Maria L. Nogal,Aitor G. Granja,María Eugenia González,Pedro Gónzalez-Porqué,Yolanda Revilla,Angel L. Carrascosa +8 more
TL;DR: The overall results likely indicate that a cellular factor/function might be the target of the antiviral action of alkyl gallates.
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Laboratory methods to study African swine fever virus.
TL;DR: Findings of comparative studies in different cells cultures susceptible to ASFV infection are summarized, through the analysis of virus components and infectious virus particles production, as alternative means to grow field and laboratory AsFV strains.